SCHEMBL11026436

SCHEMBL11026436

Clc1ccc(-c2ccccc2I)cc1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.50
PTGS2 P35354 2/20 0.47
PTGS1 P23219 1/20 0.47
SLC6A4 P31645 1/20 0.43
SLC6A3 Q01959 1/20 0.43
CYP2A6 P11509 2/20 0.41
RAB9A P51151 4/20 0.40
TSHR P16473 3/20 0.40
NPC1 O15118 3/20 0.40
KDM4E B2RXH2 3/20 0.40
HSD17B10 Q99714 2/20 0.40
ALDH1A1 P00352 2/20 0.40
TP53 P04637 1/20 0.40
NFKB1 P19838 1/20 0.40
CASP3 P42574 1/20 0.40
NFKB2 Q00653 1/20 0.40
RELA Q04206 1/20 0.40
SENP8 Q96LD8 1/20 0.40
SENP7 Q9BQF6 1/20 0.40
SENP6 Q9GZR1 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Iodide SCHEMBL8663442 0.98 CYP1A2 (0.48) CYP1A2PTGS2PTGS1SLC6A4SLC6A3
Biphenyl SCHEMBL10826986 0.94 CYP1A2 (0.62) CYP1A2PTGS2PTGS1SLC6A4SLC6A3
SCHEMBL27676479 0.92 CYP1A2 (0.48) CYP1A2PTGS2PTGS1SLC6A4SLC6A3
SCHEMBL25183913 0.83 CYP1A2 (0.38) CYP1A2PTGS2PTGS1SLC6A4SLC6A3
SCHEMBL9862848 0.82 CYP1A2 (0.63) CYP1A2PTGS2PTGS1SLC6A4SLC6A3
SCHEMBL25576173 0.81 CYP1A2 (0.41) CYP1A2PTGS2PTGS1SLC6A4SLC6A3
SCHEMBL30415853 0.81 CYP1A2 (0.41) CYP1A2PTGS2PTGS1SLC6A4SLC6A3
Trifluoromethanesulfonic Acid SCHEMBL8735178 0.81 PTGS2 (0.45) CYP1A2PTGS2PTGS1SLC6A4SLC6A3
SCHEMBL9807036 0.80 ALDH1A1 (0.33) CYP1A2PTGS2CYP2A6HSD17B10ALDH1A1
SCHEMBL6830189 0.80 ALDH1A1 (0.47) CYP1A2PTGS2CYP2A6RAB9ANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114573546-B Organic compound and organic electroluminescent element comprising same 材料科学有限公司 2024-02-23 CN disclosed
WO-2023288103-A1 METHODS FOR PREPARING LIPOSOMAL FORMULATIONS CELATOR PHARMACEUTICALS, INC. (US) 2023-01-19 WO disclosed
WO-2023288100-A1 LIPOSOMAL FORMULATIONS OF BCL INHIBITORS CELATOR PHARMACEUTICALS, INC. (US) 2023-01-19 WO disclosed
CN-114573546-A Organic compound and organic electroluminescent element comprising same 材料科学有限公司 2022-06-03 CN disclosed
EP-0061898-B1 VISIBLE LIGHT SENSITIVE, THERMALLY DEVELOPABLE IMAGING SYSTEMS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1985-06-19 EP disclosed
US-4460677-A Visible light sensitive, thermally developable imaging systems MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1984-07-17 US disclosed
US-4386154-A ACYLATED LEUCO DYES MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1983-05-31 US disclosed
EP-0061898-A1 Visible light sensitive, thermally developable imaging systems MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1982-10-06 EP disclosed