Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 4/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.37 |
| ▸ | SRC | P12931 | 1/20 | 0.37 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.37 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.37 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoromethanesulfonic Acid SCHEMBL8735155 | 0.87 | PTPN1 (0.37) | PTGS2PTGS1PTPN1ALDH1A1HSP90AA1 | |
| Trifluoromethanesulfonic Acid SCHEMBL30131111 | 0.87 | PTPN1 (0.42) | PTGS2SLC6A4SLC6A3PTPN1ALDH1A1 | |
| Trifluoromethanesulfonic Acid SCHEMBL4660340 | 0.87 | PTPN1 (0.42) | PTGS2SLC6A4SLC6A3PTPN1ALDH1A1 | |
| Trifluoromethanesulfonic Acid SCHEMBL1805194 | 0.86 | PTGS2 (0.46) | PTGS2PTGS1SLC6A4SLC6A3PDK2 | |
| Trifluoromethanesulfonic Acid SCHEMBL8737223 | 0.84 | POLB (0.40) | PTGS2PTGS1PDK2MAPTTP53 | |
| Trifluoromethanesulfonic Acid SCHEMBL1270052 | 0.82 | HSD11B1 (0.40) | TP53PTPN1ALDH1A1RAB9ANPC1 | |
| SCHEMBL11026436 | 0.81 | CYP1A2 (0.50) | PTGS2PTGS1SLC6A4SLC6A3MAPT | |
| Trifluoromethanesulfonic Acid SCHEMBL387254 | 0.81 | HDAC4 (0.47) | PTGS2PDK2MAPTTP53FGFR1 | |
| Trifluoromethanesulfonic Acid SCHEMBL3987054 | 0.80 | PTGS2 (0.40) | PTGS2MAPTALDH1A1SMN1; SMN2TDP1 | |
| Iodide SCHEMBL8663442 | 0.79 | CYP1A2 (0.48) | PTGS2PTGS1SLC6A4SLC6A3MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0697387-B1 | Improved method for the preparation of iodonium salts | DOW CORNING (US) | 1998-04-22 | — | — | EP | disclosed |