Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.43 |
| ▸ | TBXA2R | P21731 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | TBXAS1 | P24557 | 3/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | RHOC | P08134 | 1/20 | 0.41 |
| ▸ | RHOA | P61586 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10671693 | 0.85 | NPSR1 (0.48) | CES2KMT2AMEN1NPSR1LMNA | |
| SCHEMBL9799633 | 0.84 | PARP1 (0.46) | KMT2AMEN1ALDH1A1POLB | |
| SCHEMBL9799689 | 0.83 | L3MBTL1 (0.43) | KMT2AMAPK1ALDH1A1POLB | |
| SCHEMBL10668346 | 0.83 | F2 (0.51) | CES2KMT2AMEN1NPSR1LMNA | |
| SCHEMBL10669808 | 0.82 | NPSR1 (0.48) | CES2KMT2AMEN1NPSR1LMNA | |
| SCHEMBL9865405 | 0.77 | IDO1 (0.47) | CES2KMT2ALMNASRD5A2TBXA2R | |
| SCHEMBL9864560 | 0.76 | CES2 (0.42) | CES2KMT2ANPSR1LMNATBXA2R | |
| SCHEMBL9799575 | 0.76 | PLOD2 (0.41) | CES2KMT2ALMNAPOLBMAOB | |
| SCHEMBL11038316 | 0.76 | PLOD2 (0.41) | CES2KMT2ALMNAPOLBMAOB | |
| SCHEMBL11040229 | 0.75 | L3MBTL1 (0.43) | KMT2AMEN1NPSR1LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0094348-B1 | OXIME ETHERS, PROCESS FOR THEIR PREPARATION, AGENTS CONTAINING THE OXIME ETHERS AND THEIR USE | CIBA-GEIGY AG (CH) | 1985-07-24 | — | — | EP | claimed |