Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | ALB | P02768 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.46 |
| ▸ | HBB | P68871 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | TK2 | O00142 | 2/20 | 0.45 |
| ▸ | TYMP | P19971 | 1/20 | 0.43 |
| ▸ | TK1 | P04183 | 3/20 | 0.43 |
| ▸ | PYGM | P11217 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20846987 | 0.89 | LMNA (0.45) | LMNAALDH1A1ALBPOLBADRA1A | |
| SCHEMBL11022514 | 0.87 | LMNA (0.44) | LMNAALDH1A1ALBPOLBADRA1A | |
| SCHEMBL11022486 | 0.86 | TK2 (0.51) | LMNAALDH1A1ALBPOLBADRA1A | |
| SCHEMBL15164434 | 0.85 | LMNA (0.50) | LMNAALDH1A1ALBPOLBADRA1A | |
| SCHEMBL8612661 | 0.84 | RNASE1 (0.44) | LMNAALDH1A1ALBPOLBADRA1A | |
| SCHEMBL4653181 | 0.84 | TK1 (0.45) | LMNAALDH1A1ALBPOLBADRA1A | |
| SCHEMBL8422441 | 0.83 | LMNA (0.52) | LMNAALDH1A1ALBPOLBADRA1A | |
| SCHEMBL8422445 | 0.83 | LMNA (0.52) | LMNAALDH1A1ALBPOLBADRA1A | |
| SCHEMBL932061 | 0.79 | LMNA (0.43) | LMNAALDH1A1ALBPOLBADRA1A | |
| SCHEMBL11404005 | 0.79 | DNPH1 (0.45) | LMNAALDH1A1ALBPOLBADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0056265-B1 | PYRIMIDINENUCLEOSIDES ESTERIFIED IN POSITION 5' HAVING ANTIVIRAL ACTIVITY, METHOD FOR THEIR PREPARATION AND MEDICINAL COMPOSITIONS CONTAINING THEM | Dr. Thilo & Co. GmbH (DE) | 1985-05-15 | — | — | EP | claimed |