Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.37 |
| ▸ | MGAM | O43451 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | SI | P14410 | 1/20 | 0.35 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
| ▸ | GSK3A | P49840 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 3/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.32 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.31 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.31 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.31 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.31 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.31 |
| ▸ | PGR | P06401 | 1/20 | 0.31 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11030953 | 1.00 | ALDH1A1 (0.37) | ALDH1A1TRPA1MGAMGAASI | |
| SCHEMBL5686103 | 0.84 | TRPA1 (0.35) | ALDH1A1TRPA1MGAMGAASI | |
| SCHEMBL5686106 | 0.84 | TRPA1 (0.35) | ALDH1A1TRPA1MGAMGAASI | |
| SCHEMBL5683344 | 0.81 | GAA (0.35) | ALDH1A1TRPA1MGAMGAASI | |
| SCHEMBL5683340 | 0.81 | GAA (0.35) | ALDH1A1TRPA1MGAMGAASI | |
| SCHEMBL9796686 | 0.76 | GAA (0.40) | ALDH1A1TRPA1MGAMGAASI | |
| SCHEMBL9796681 | 0.76 | GAA (0.40) | ALDH1A1TRPA1MGAMGAASI | |
| SCHEMBL9796701 | 0.75 | GAA (0.43) | ALDH1A1TRPA1MGAMGAASI | |
| SCHEMBL9796704 | 0.75 | GAA (0.43) | ALDH1A1TRPA1MGAMGAASI | |
| SCHEMBL9796984 | 0.75 | ALDH1A1 (0.45) | ALDH1A1TRPA1MGAMGAASI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0043143-B1 | PROCESS FOR STEREOSELECTIVELY SYNTHETIZING CYCLOPROPANE CARBOXYLATES AS INTERMEDIATES FOR PYRETHROIDS | Montedison S.p.A. (IT) | 1985-06-19 | — | — | EP | disclosed |
| US-4442301-A | DEHYDROHALOGENATION, CYCLIZATION | MONTEDISON S.P.A. (IT) | 1984-04-10 | — | — | US | disclosed |
| EP-0043143-A2 | Process for stereoselectively synthetizing cyclopropane carboxylates as intermediates for pyrethroids | Montedison S.p.A. (IT) | 1982-01-06 | — | — | EP | disclosed |