Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 7/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.45 |
| ▸ | RAB9A | P51151 | 5/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | JMJD6 | Q6NYC1 | 1/20 | 0.44 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.44 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9750298 | 0.84 | RARA (0.50) | LMNAKMT2AMAPTALDH1A1RAB9A | |
| SCHEMBL10882529 | 0.79 | NOX1 (0.46) | KMT2ATDP1MAPTALDH1A1RAB9A | |
| SCHEMBL13171960 | 0.78 | NR1H2 (0.45) | LMNAKMT2ATDP1MAPTKDM4E | |
| SCHEMBL9750432 | 0.77 | HRH3 (0.48) | KMT2ARAB9ANPC1SRD5A2MEN1 | |
| SCHEMBL10939899 | 0.76 | ALDH1A1 (0.52) | LMNAKMT2ATDP1SLC6A2SLC6A3 | |
| SCHEMBL8839024 | 0.72 | KMT2A (0.56) | LMNAKMT2ATDP1SLC6A2SLC6A3 | |
| SCHEMBL7927907 | 0.71 | SRD5A1 (0.55) | LMNAKMT2ATDP1SLC6A2SLC6A3 | |
| SCHEMBL9750023 | 0.71 | RARA (0.47) | LMNAKMT2AMAPTALDH1A1RAB9A | |
| SCHEMBL312287 | 0.70 | KMT2A (0.92) | LMNAKMT2ATDP1SLC6A2SLC6A3 | |
| SCHEMBL23222980 | 0.70 | TDP1 (0.57) | LMNAKMT2ATDP1SLC6A2SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0074569-B1 | CATIONIC METHINE DYES, PROCESS FOR THEIR PREPARATION AND THEIR USE, IN DYEING TEXTILE MATERIALS AND OTHER SUBSTRATES | BAYER AG (DE) | 1985-06-19 | — | — | EP | disclosed |
| EP-0074569-A2 | Cationic methine dyes, process for their preparation and their use, in dyeing textile materials and other substrates | BAYER AG (DE) | 1983-03-23 | — | — | EP | disclosed |