SCHEMBL11028628

SCHEMBL11028628

COC(=O)C(O)(OC)C(C)=O

nearest known ligand 0.38

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.38
DGAT1 O75907 1/20 0.36
SRC P12931 1/20 0.33
KCNN4 O15554 1/20 0.32
MGAM O43451 1/20 0.31
GAA P10253 1/20 0.31
SI P14410 1/20 0.31
MGAM2 Q2M2H8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12083395 0.72 ALDH1A1 (0.42) ALDH1A1DGAT1SRCKCNN4MGAM
SCHEMBL28175501 0.72 ALDH1A1 (0.42) ALDH1A1DGAT1SRCKCNN4MGAM
SCHEMBL134110 0.71
SCHEMBL17826670 0.70 DGAT1 (0.42) ALDH1A1DGAT1SRCKCNN4MGAM
SCHEMBL28668019 0.70 ALDH1A1 (0.40) ALDH1A1DGAT1SRCKCNN4MGAM
SCHEMBL2552792 0.70 DGAT1 (0.42) ALDH1A1DGAT1SRCKCNN4MGAM
SCHEMBL11422045 0.69 ALDH1A1 (0.44) ALDH1A1DGAT1SRCKCNN4MGAM
SCHEMBL18868424 0.69 ALDH1A1 (0.44) ALDH1A1DGAT1SRCKCNN4MGAM
Methyl Alcohol SCHEMBL28262055 0.69 DGAT1 (0.46) ALDH1A1DGAT1SRCKCNN4
SCHEMBL14946214 0.68 DGAT1 (0.41) ALDH1A1DGAT1KCNN4MGAMGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4501917-A REACTING WITH CARBON MONOXIDE; CATALYST IS ACID ORGANIC ION EXCHANGE MATERIAL HOECHST AKTIENGESELLSCHAFT (DE) 1985-02-26 US disclosed