SCHEMBL2552792

SCHEMBL2552792

COC(=O)C(C)(O)C(C)=O

nearest known ligand 0.42

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
DGAT1 O75907 1/20 0.42
ALDH1A1 P00352 4/20 0.40
TSHR P16473 3/20 0.35
SRC P12931 1/20 0.34
MAPT P10636 1/20 0.34
KCNN4 O15554 1/20 0.33
GAA P10253 2/20 0.32
MGAM O43451 1/20 0.32
SI P14410 1/20 0.32
MGAM2 Q2M2H8 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17826670 1.00 DGAT1 (0.42) DGAT1ALDH1A1TSHRSRCMAPT
SCHEMBL11275466 0.90 DGAT1 (0.39) DGAT1ALDH1A1TSHRSRCMAPT
SCHEMBL9692472 0.79 ALDH1A1 (0.40) DGAT1ALDH1A1SRCMAPTKCNN4
SCHEMBL4070809 0.78 ALDH1A1 (0.45) DGAT1ALDH1A1TSHRSRCMAPT
SCHEMBL22433018 0.76 DGAT1 (0.41) DGAT1ALDH1A1TSHRSRCKCNN4
SCHEMBL16599779 0.75
SCHEMBL1661824 0.74 DGAT1 (0.44) DGAT1ALDH1A1TSHRSRCMAPT
SCHEMBL1022153 0.74 DGAT1 (0.56) DGAT1ALDH1A1TSHRSRCMAPT
SCHEMBL12083395 0.74 ALDH1A1 (0.42) DGAT1ALDH1A1TSHRSRCMAPT
SCHEMBL13646326 0.74

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2553145-B1 ETCH RESISTANT ALUMINA BASED COATINGS PIBOND OY (FI) 2022-09-21 EP disclosed
EP-2764052-B1 IRON(III) CONTAINING COMPLEX AND CONDENSATION REACTION CATALYSTS, METHODS FOR PREPARING THE CATALYSTS, AND COMPOSITIONS CONTAINING THE CATALYSTS DOW SILICONES CORP (US) 2018-07-18 EP disclosed
US-20170200615-A1 ETCH RESISTANT ALUMINA BASED COATINGS PIBOND (ZHEJIANG) NEW MATERIALS CO., LTD (CN) 2017-07-13 US disclosed
US-9564339-B2 Etch resistant alumina based coatings PIBOND OY (FI) 2017-02-07 US disclosed
US-9328205-B2 Iron(III) containing complex and condensation reaction catalysts, methods for preparing the catalysts, and compositions containing the catalysts DOW CORNING CORPORATION (US) 2016-05-03 US disclosed
US-9328205-B2 Iron(III) containing complex and condensation reaction catalysts, methods for preparing the catalysts, and compositions containing the catalysts DOW CORNING CORPORATION (US) 2016-05-03 US disclosed
US-9328205-B2 Iron(III) containing complex and condensation reaction catalysts, methods for preparing the catalysts, and compositions containing the catalysts DOW CORNING CORPORATION (US) 2016-05-03 US disclosed
EP-2903586-A2 COMPOSITION Trigiante, Giuseppe (GB) 2015-08-12 EP disclosed
US-20140371056-A1 Iron(III) Containing Complex and Condensation Reaction Catalysts, Methods for Preparing the Catalysts, and Compositions Containing the Catalysts DOW COMING CORPORATION (US) 2014-12-18 US disclosed
US-20140371056-A1 Iron(III) Containing Complex and Condensation Reaction Catalysts, Methods for Preparing the Catalysts, and Compositions Containing the Catalysts DOW COMING CORPORATION (US) 2014-12-18 US disclosed
US-7939685-B2 Hydroxylation of β-dicarbonyls with zirconium catalysts E. I. DU PONT DE NEMOURS AND COMPANY (US) 2011-05-10 US disclosed
US-7939685-B2 Hydroxylation of β-dicarbonyls with zirconium catalysts E. I. DU PONT DE NEMOURS AND COMPANY (US) 2011-05-10 US disclosed
US-20100185014-A1 Hydroxylation of Beta-Dicarbonyls with Zirconium Catalysts FMC CORPORATION 2010-07-22 US disclosed
US-20100185014-A1 Hydroxylation of Beta-Dicarbonyls with Zirconium Catalysts FMC CORPORATION 2010-07-22 US disclosed
US-7718818-B2 Hydroxylation of beta-dicarbonyls with zirconium catalysts E.I. DU PONT DE NEMOURS AND COMPANY (US) 2010-05-18 US disclosed
US-7718818-B2 Hydroxylation of beta-dicarbonyls with zirconium catalysts E.I. DU PONT DE NEMOURS AND COMPANY (US) 2010-05-18 US disclosed
US-20080306259-A1 HYDROXYLATION OF BETA-DICARBONYLS WITH ZIRCONIUM CATALYSTS FMC CORPORATION 2008-12-11 US disclosed
US-20080306259-A1 HYDROXYLATION OF BETA-DICARBONYLS WITH ZIRCONIUM CATALYSTS FMC CORPORATION 2008-12-11 US disclosed
US-7414157-B2 Hydroxylation of β-dicarbonyls with zirconium catalysts E. I. DU PONT DE NEMOURS AND COMPANY (US) 2008-08-19 US disclosed
US-7414157-B2 Hydroxylation of β-dicarbonyls with zirconium catalysts E. I. DU PONT DE NEMOURS AND COMPANY (US) 2008-08-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100185014-A1 Hydroxylation of Beta-Dicarbonyls with Zirconium Catalysts CBR3, CBR1, NOXO1 DGAT1 1727/4885ALDH1A1 258/4885TSHR 3292/4885
US-20080306259-A1 HYDROXYLATION OF BETA-DICARBONYLS WITH ZIRCONIUM CATALYSTS CBR3, CBR1, ASPH DGAT1 2218/4885ALDH1A1 260/4885TSHR 3942/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.