Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.32 |
| ▸ | HPGD | P15428 | 3/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | MPO | P05164 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.30 |
| ▸ | DAO | P14920 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11028566 | 0.91 | KMT2A (0.36) | ALDH1A1TDP1KMT2AL3MBTL1HPGD | |
| SCHEMBL11027929 | 0.90 | ALDH1A1 (0.36) | ALDH1A1TDP1HTTMAPTNPC1 | |
| SCHEMBL11157287 | 0.81 | DAO (0.33) | ALDH1A1RAB9AKMT2AL3MBTL1SMN1; SMN2 | |
| SCHEMBL10351408 | 0.74 | GAA (0.32) | ALDH1A1TDP1 | |
| SCHEMBL11029494 | 0.69 | PKM (0.34) | ALDH1A1KMT2AL3MBTL1LMNAMPO | |
| SCHEMBL11028987 | 0.68 | GAA (0.33) | SMN1; SMN2 | |
| SCHEMBL11158949 | 0.67 | MAPT (0.44) | ALDH1A1TDP1MAPTNPC1RAB9A | |
| SCHEMBL11028741 | 0.66 | L3MBTL1 (0.42) | ALDH1A1TDP1HTTMAPTNPC1 | |
| SCHEMBL11029993 | 0.66 | ALDH1A1 (0.43) | ALDH1A1TDP1HTTMAPTNPC1 | |
| SCHEMBL27833841 | 0.65 | KMT2A (0.38) | ALDH1A1TDP1KMT2AL3MBTL1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0078784-B1 | THIO-SUBSTITUTED-1,3,5-TRIAZINE-DIAMINES AND -TRIAMINES USEFUL AS PREVULCANIZATION INHIBITORS | MONSANTO COMPANY (US) | 1985-07-03 | — | — | EP | disclosed |
| US-4460769-A | Thio-amino-1,3,5-triazines | MONSANTO COMPANY (US) | 1984-07-17 | — | — | US | disclosed |
| EP-0078784-A1 | Thio-substituted-1,3,5-triazine-diamines and -triamines useful as prevulcanization inhibitors | MONSANTO COMPANY (US) | 1983-05-11 | — | — | EP | disclosed |
| US-4380609-A | Prevulcanization inhibitors of thio-triazine-amines for rubber | MONSANTO COMPANY (US) | 1983-04-19 | — | — | US | disclosed |