Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MPO | P05164 | 1/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.33 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
| ▸ | DAO | P14920 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.32 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11029045 | 0.91 | ALDH1A1 (0.41) | KMT2AL3MBTL1KDM4EALDH1A1MPO | |
| SCHEMBL11157287 | 0.89 | DAO (0.33) | KMT2AL3MBTL1KDM4EALDH1A1MPO | |
| SCHEMBL11029494 | 0.76 | PKM (0.34) | KMT2AL3MBTL1ALDH1A1MPOCYP2D6 | |
| SCHEMBL11028741 | 0.72 | L3MBTL1 (0.42) | KMT2AL3MBTL1ALDH1A1MEN1TDP1 | |
| SCHEMBL775627 | 0.68 | KMT2A (0.45) | KMT2AL3MBTL1KDM4EALDH1A1TAAR1 | |
| SCHEMBL577805 | 0.68 | ALDH1A1 (0.46) | KMT2AL3MBTL1KDM4EALDH1A1TAAR1 | |
| SCHEMBL14535430 | 0.66 | KMT2A (0.44) | KMT2AL3MBTL1KDM4EALDH1A1TAAR1 | |
| SCHEMBL20809867 | 0.66 | KMT2A (0.44) | KMT2AL3MBTL1KDM4EALDH1A1TAAR1 | |
| SCHEMBL1145689 | 0.66 | KMT2A (0.44) | KMT2AL3MBTL1KDM4EALDH1A1TAAR1 | |
| SCHEMBL24302355 | 0.64 | ADRA2C (0.44) | KMT2AL3MBTL1KDM4EALDH1A1TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0078784-B1 | THIO-SUBSTITUTED-1,3,5-TRIAZINE-DIAMINES AND -TRIAMINES USEFUL AS PREVULCANIZATION INHIBITORS | MONSANTO COMPANY (US) | 1985-07-03 | — | — | EP | disclosed |
| US-4460769-A | Thio-amino-1,3,5-triazines | MONSANTO COMPANY (US) | 1984-07-17 | — | — | US | disclosed |
| EP-0078784-A1 | Thio-substituted-1,3,5-triazine-diamines and -triamines useful as prevulcanization inhibitors | MONSANTO COMPANY (US) | 1983-05-11 | — | — | EP | disclosed |
| US-4380609-A | Prevulcanization inhibitors of thio-triazine-amines for rubber | MONSANTO COMPANY (US) | 1983-04-19 | — | — | US | disclosed |