Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.47 |
| ▸ | PPARD | Q03181 | 1/20 | 0.44 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | ELANE | P08246 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11029455 | 0.79 | KDM4E (0.47) | KDM4EGABRA1GABRB2ALDH1A1SMN1; SMN2 | |
| SCHEMBL23457204 | 0.78 | KDM4E (0.47) | KDM4EPPARDALDH1A1SMN1; SMN2L3MBTL1 | |
| SCHEMBL150621 | 0.78 | ALDH1A1 (0.45) | KDM4EPPARDGABRA1GABRB2ALDH1A1 | |
| SCHEMBL3458335 | 0.78 | GABRA1 (0.51) | KDM4EGABRA1GABRB2ALDH1A1MAPK1 | |
| SCHEMBL15283972 | 0.77 | LMNA (0.50) | KDM4EPPARDALDH1A1SMN1; SMN2L3MBTL1 | |
| SCHEMBL14695733 | 0.76 | GABRA1 (0.53) | KDM4EGABRA1GABRB2ALDH1A1SMN1; SMN2 | |
| SCHEMBL10433454 | 0.76 | KDM4E (0.56) | KDM4EGABRA1GABRB2ALDH1A1SMN1; SMN2 | |
| SCHEMBL7856426 | 0.75 | PTGDR2 (0.56) | KDM4EGABRA1GABRB2ALDH1A1SMN1; SMN2 | |
| SCHEMBL7856423 | 0.74 | GABRA1 (0.53) | KDM4EGABRA1GABRB2SMN1; SMN2MAPK1 | |
| SCHEMBL2848296 | 0.73 | GABRA1 (0.49) | KDM4EGABRA1GABRB2ALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-60127317-A | — | — | None | — | — | JP | disclosed |
| JP-S60127317-A | MANUFACTURE OF CURABLE COMPOSITION | TOAGOSEI CHEM IND CO LTD | 1985-07-08 | — | — | JP | disclosed |