Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.59 |
| ▸ | RAB9A | P51151 | 5/20 | 0.59 |
| ▸ | MEN1 | O00255 | 5/20 | 0.59 |
| ▸ | NPC1 | O15118 | 4/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | CASP3 | P42574 | 1/20 | 0.59 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.59 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.59 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.59 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.54 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.54 |
| ▸ | CNR1 | P21554 | 4/20 | 0.54 |
| ▸ | MAOA | P21397 | 1/20 | 0.53 |
| ▸ | MAOB | P27338 | 1/20 | 0.53 |
| ▸ | FPR2 | P25090 | 1/20 | 0.51 |
| ▸ | MTOR | P42345 | 1/20 | 0.48 |
| ▸ | NAMPT | P43490 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10548838 | 0.87 | CNR1 (0.66) | KMT2ARAB9AMEN1NPC1ROCK2 | |
| SCHEMBL11027327 | 0.84 | RAB9A (0.64) | KMT2ARAB9AMEN1NPC1LMNA | |
| SCHEMBL11029559 | 0.83 | KMT2A (0.57) | KMT2ARAB9AMEN1NPC1MAPT | |
| SCHEMBL11031455 | 0.82 | NPC1 (0.60) | KMT2ARAB9AMEN1NPC1ROCK2 | |
| SCHEMBL5638898 | 0.81 | NAMPT (0.60) | KMT2AMEN1ROCK2ROCK1NAMPT | |
| SCHEMBL11051112 | 0.81 | RAB9A (0.60) | KMT2ARAB9AMEN1NPC1LMNA | |
| SCHEMBL10545814 | 0.81 | TAS1R3 (0.61) | KMT2ARAB9AMEN1LMNAMAPT | |
| SCHEMBL27942206 | 0.78 | KMT2A (0.69) | KMT2ARAB9AMEN1NPC1MAPT | |
| SCHEMBL11029084 | 0.77 | NPC1 (0.53) | KMT2ARAB9AMEN1NPC1MAPT | |
| SCHEMBL11050914 | 0.76 | CNR1 (0.66) | KMT2ARAB9AMEN1NPC1CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4438110-A | 1-(MONO-SUBSTITUTED PHENYL)-3-BENZOYL UREA AND A PHOSPHOROUS CONTAINING COMPOUND | UNION CARBIDE CORPORATION (US) | 1984-03-20 | — | — | US | disclosed |