Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESRRA | P11474 | 2/20 | 0.56 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.48 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.47 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.47 |
| ▸ | ITGAL | P20701 | 1/20 | 0.47 |
| ▸ | KDM1A | O60341 | 1/20 | 0.45 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | RHEB | Q15382 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.41 |
| ▸ | STK39 | Q9UEW8 | 3/20 | 0.40 |
| ▸ | HTR1B | P28222 | 2/20 | 0.40 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.39 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.39 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.39 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10884537 | 0.98 | ESRRA (0.54) | ESRRASCN9AITGB2ICAM1ITGAL | |
| SCHEMBL10963610 | 0.83 | ESRRA (0.54) | ESRRAITGB2ICAM1ITGALHPGD | |
| SCHEMBL10359650 | 0.83 | ALDH1A1 (0.44) | ESRRAKDM1ARCOR1HPGDCYP1A2 | |
| SCHEMBL632218 | 0.83 | CYP3A4 (0.46) | HPGDRHEBCYP3A4TSHRALDH1A1 | |
| SCHEMBL11029673 | 0.82 | ESRRA (0.47) | ESRRASCN9AITGB2ICAM1ITGAL | |
| SCHEMBL11029113 | 0.81 | ESRRA (0.43) | ESRRAHPGDCYP1A2CYP2A6HTR1B | |
| SCHEMBL15084627 | 0.81 | TRPA1 (0.48) | ESRRASCN9AKDM1ARCOR1HPGD | |
| SCHEMBL10961278 | 0.81 | IDO1 (0.51) | ESRRACYP3A4ALDH1A1GAA | |
| SCHEMBL1964539 | 0.80 | CYP3A4 (0.56) | ITGB2ICAM1ITGALHPGDCYP3A4 | |
| SCHEMBL22069692 | 0.78 | RHEB (0.45) | HPGDRHEBCYP3A4TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100004238-A1 | FUSED HETEROCYCLIC COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-01-07 | — | — | US | disclosed |
| EP-2103620-A1 | FUSED HETEROCYCLIC COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2009-09-23 | — | — | EP | disclosed |
| WO-2005007083-A2 | CHEMICAL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2005-01-27 | — | — | WO | disclosed |
| WO-2004112714-A2 | CHEMICAL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2004-12-29 | — | — | WO | disclosed |
| EP-0081743-B1 | NAPHTHOXYPHENYL UREAS, PROCESS FOR THEIR PREPARATION AND THEIR USE AS HERBICIDES | BASF Aktiengesellschaft (DE) | 1986-05-14 | — | — | EP | disclosed |
| EP-0081743-A2 | Naphthoxyphenyl ureas, process for their preparation and their use as herbicides | BASF Aktiengesellschaft (DE) | 1983-06-22 | — | — | EP | disclosed |
| EP-0013414-B1 | UREA DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS INSECTICIDES | CELAMERCK GmbH & Co. KG (DE) | 1982-06-23 | — | — | EP | disclosed |
| EP-0050321-A2 | Novel bicyclooxyphenyl ureas, process for their preparation and pesticides containing them | UNION CARBIDE CORPORATION (US) | 1982-04-28 | — | — | EP | disclosed |
| US-4275077-A | Insecticidal acyl urea derivatives | CELAMERCK GMBH & CO. KG (DE) | 1981-06-23 | — | — | US | disclosed |
| EP-0013414-A2 | Urea derivatives, process for their preparation and their use as insecticides | CELAMERCK GmbH & Co. KG (DE) | 1980-07-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100004238-A1 | FUSED HETEROCYCLIC COMPOUND | ERBB2, ROS1, FLT3 | ESRRA 1149/4885SCN9A 3444/4885ITGB2 2771/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.