Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTRB1 | P17538 | 2/20 | 0.56 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.51 |
| ▸ | CTSL | P07711 | 3/20 | 0.51 |
| ▸ | TACR1 | P25103 | 3/20 | 0.50 |
| ▸ | ECE1 | P42892 | 3/20 | 0.49 |
| ▸ | CTSS | P25774 | 2/20 | 0.49 |
| ▸ | CTSB | P07858 | 1/20 | 0.49 |
| ▸ | CTSK | P43235 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 1/20 | 0.49 |
| ▸ | MME | P08473 | 1/20 | 0.48 |
| ▸ | ITGB3 | P05106 | 4/20 | 0.48 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6850692 | 0.90 | CTRB1 (0.59) | CTRB1TRPM8CTSLTACR1ECE1 | |
| SCHEMBL7701531 | 0.90 | CTRB1 (0.59) | CTRB1TRPM8CTSLTACR1ECE1 | |
| SCHEMBL29467644 | 0.84 | CTRB1 (0.60) | CTRB1TRPM8CTSLTACR1CTSS | |
| SCHEMBL20529450 | 0.84 | CTRB1 (0.60) | CTRB1TRPM8CTSLTACR1CTSS | |
| SCHEMBL7886288 | 0.84 | CTRB1 (0.60) | CTRB1TRPM8CTSLTACR1CTSS | |
| SCHEMBL3482895 | 0.82 | CTRB1 (0.57) | CTRB1TRPM8CTSLTACR1ECE1 | |
| SCHEMBL10801569 | 0.82 | MMP8 (0.54) | CTRB1TRPM8CTSLECE1CTSS | |
| SCHEMBL9737911 | 0.82 | ATM (0.54) | CTSLCTSSCTSBCTSK | |
| SCHEMBL10993222 | 0.81 | CTSL (0.54) | CTRB1CTSLTACR1ECE1CTSS | |
| SCHEMBL11785122 | 0.81 | CTSL (0.60) | CTRB1TRPM8CTSLCTSSCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0099960-B1 | PROCESS FOR THE PREPARATION OF LOWER ALKYL ESTERS OF N-L-ALPHA-ASPARTYL-L-PHENYL ALANINE, AND INTERMEDIATES FOR THEIR MANUFACTURE | EPROVA AG Forschungsinstitut (CH) | 1985-04-10 | — | — | EP | disclosed |