Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTRB1 | P17538 | 2/20 | 0.59 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.54 |
| ▸ | TACR1 | P25103 | 2/20 | 0.53 |
| ▸ | CTSL | P07711 | 3/20 | 0.52 |
| ▸ | CTSS | P25774 | 3/20 | 0.52 |
| ▸ | CTSB | P07858 | 2/20 | 0.52 |
| ▸ | CTSK | P43235 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | ECE1 | P42892 | 3/20 | 0.51 |
| ▸ | MME | P08473 | 3/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6850692 | 1.00 | CTRB1 (0.59) | CTRB1TRPM8TACR1CTSLCTSS | |
| SCHEMBL11029773 | 0.90 | CTRB1 (0.56) | CTRB1TRPM8TACR1CTSLCTSS | |
| SCHEMBL29467644 | 0.88 | CTRB1 (0.60) | CTRB1TRPM8TACR1CTSLCTSS | |
| SCHEMBL7886288 | 0.88 | CTRB1 (0.60) | CTRB1TRPM8TACR1CTSLCTSS | |
| SCHEMBL20529450 | 0.88 | CTRB1 (0.60) | CTRB1TRPM8TACR1CTSLCTSS | |
| SCHEMBL7759227 | 0.87 | ECE1 (0.62) | CTRB1CTSLCTSSCTSBCTSK | |
| SCHEMBL11785122 | 0.87 | CTSL (0.60) | CTRB1TRPM8CTSLCTSSCTSB | |
| SCHEMBL11148538 | 0.87 | MME (0.58) | CTRB1TACR1CTSLCTSSCTSB | |
| SCHEMBL7757920 | 0.86 | MME (0.59) | CTSLCTSSECE1MME | |
| SCHEMBL8909917 | 0.86 | CTRB1 (0.51) | CTRB1TRPM8CTSLCTSSCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4356499-A | — | — | None | — | — | JP | disclosed |
| US-6342582-B1 | PURIFICATION AND/OR BIOSYNTHESIS OF OLIGOPEPTIDES IN PRESENCE OF A PHENOL OR MIXTURE; DEBLOCKING, AMIDATION; VACCINES, DRUGS, FOOD, AGRICULTURE | RHODIA CHIMIE (FR) | 2002-01-29 | — | — | US | disclosed |
| US-5798443-A | MEDIUM COMPRISING WATER IMMISCIBLE DILUENT AND HYDROXYAROMATIC COMPOUND | RHONE-POULENC CHIMIE (FR) | 1998-08-25 | — | — | US | disclosed |
| JP-H04356499-A | PRODUCTION OF PHYSIOLOGICALLY ACTIVE PENTAPEPTIDE | TANABE SEIYAKU CO LTD | 1992-12-10 | — | — | JP | disclosed |
| US-4119493-A | IN PRESENCE OF METALLOPROTEINASE ENZYME | (ZAIDANHOJIN) SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1978-10-10 | — | — | US | disclosed |
| US-4116768-A | AMIDATION, METALLOPROTEINASE ENZYME | (ZAIDANHOJIN) SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1978-09-26 | — | — | US | disclosed |