Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.51 |
| ▸ | NPC1 | O15118 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.43 |
| ▸ | RELA | Q04206 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11031950 | 0.84 | TSHR (0.41) | RAB9ANPC1ALDH1A1KMT2AKDM4E | |
| SCHEMBL11059263 | 0.79 | KMT2A (0.45) | RAB9ANPC1ALDH1A1PPARGKMT2A | |
| SCHEMBL11054339 | 0.79 | LMNA (0.47) | ALDH1A1KMT2AMEN1KDM4EHPGD | |
| SCHEMBL10697512 | 0.76 | ALDH1A1 (0.54) | RAB9ANPC1ALDH1A1PPARGKCNA5 | |
| SCHEMBL694862 | 0.73 | PKM (0.67) | ALDH1A1PPARGKMT2APKMHSD17B10 | |
| SCHEMBL15869671 | 0.72 | KDM4E (0.58) | RAB9APKMKDM4ETHRBMAPT | |
| Lithium Ion SCHEMBL28703021 | 0.72 | KMT2A (0.46) | ALDH1A1KMT2AMEN1KDM4EHPGD | |
| SCHEMBL28920767 | 0.72 | KMT2A (0.46) | ALDH1A1KMT2AMEN1KDM4EHPGD | |
| SCHEMBL29113266 | 0.72 | KMT2A (0.46) | ALDH1A1KMT2AMEN1KDM4EHPGD | |
| SCHEMBL29113268 | 0.72 | KMT2A (0.46) | ALDH1A1KMT2AMEN1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0049498-B1 | ALUMINIUM COMPOUNDS THAT CONTAIN AN ORGANIC REST, ANTI-SUDORIFIC AGENT CONTAINING THESE COMPOUNDS AS ACTIVE COMPONENTS AND APPLICATION OF THIS AGENT AS AN ANTI-SUDORIFIC AGENT | Richardson-Vicks, Inc. (US) | 1985-01-30 | — | — | EP | claimed |
| US-4434178-A | ORGANOALUMINUM CHLORIDE COMPOUNDS | HOFFMANN-LA ROCHE, INC. (US) | 1984-02-28 | — | — | US | claimed |
| EP-0049498-A1 | Aluminium compounds that contain an organic rest, anti-sudorific agent containing these compounds as active components and application of this agent as an anti-sudorific agent | Richardson-Vicks, Inc. (US) | 1982-04-14 | — | — | EP | claimed |
| EP-0049498-B1 | ALUMINIUM COMPOUNDS THAT CONTAIN AN ORGANIC REST, ANTI-SUDORIFIC AGENT CONTAINING THESE COMPOUNDS AS ACTIVE COMPONENTS AND APPLICATION OF THIS AGENT AS AN ANTI-SUDORIFIC AGENT | Richardson-Vicks, Inc. (US) | 1985-01-30 | — | — | EP | disclosed |
| US-4434178-A | ORGANOALUMINUM CHLORIDE COMPOUNDS | HOFFMANN-LA ROCHE, INC. (US) | 1984-02-28 | — | — | US | disclosed |
| EP-0049498-A1 | Aluminium compounds that contain an organic rest, anti-sudorific agent containing these compounds as active components and application of this agent as an anti-sudorific agent | Richardson-Vicks, Inc. (US) | 1982-04-14 | — | — | EP | disclosed |