Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.47 |
| ▸ | CASP6 | P55212 | 3/20 | 0.43 |
| ▸ | CASP3 | P42574 | 2/20 | 0.43 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.43 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.43 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | MGLL | Q99685 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 4/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.40 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.39 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7008036 | 0.86 | HPGD (0.62) | HPGDKMT2AMEN1NOTUMCASP6 | |
| SCHEMBL28207136 | 0.83 | HPGD (0.56) | HPGDKMT2AMEN1NOTUMCASP6 | |
| SCHEMBL29651988 | 0.79 | GAA (0.59) | HPGDKMT2AMEN1NOTUMCASP6 | |
| SCHEMBL2982634 | 0.79 | GAA (0.59) | HPGDKMT2AMEN1NOTUMCASP6 | |
| SCHEMBL6765903 | 0.76 | HPGD (0.74) | HPGDKMT2AMEN1NOTUMCASP6 | |
| SCHEMBL6767398 | 0.76 | HPGD (0.68) | HPGDKMT2AMEN1NOTUMCASP6 | |
| SCHEMBL143970 | 0.74 | HPGD (1.00) | HPGDKMT2AMEN1NOTUMCASP6 | |
| SCHEMBL31422646 | 0.74 | HPGD (1.00) | HPGDKMT2AMEN1NOTUMCASP6 | |
| SCHEMBL11563122 | 0.73 | HPGD (0.51) | HPGDKMT2AMEN1NOTUMCASP6 | |
| SCHEMBL7846622 | 0.72 | HPGD (0.59) | HPGDKMT2ANOTUMCASP6CASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-59020256-A | — | — | None | — | — | JP | disclosed |
| JP-59190967-A | — | — | None | — | — | JP | disclosed |
| JP-S59190967-A | 1-(2,6-DIFLUOROPHENYL)-2-INDOLINONE DERIVATIVE | HOKURIKU SEIYAKU CO LTD | 1984-10-29 | — | — | JP | disclosed |
| JP-S5920256-A | 2-(2,6-DIFLUOROANILINO)PHENYLACETIC ACID DERIVATIVE | HOKURIKU SEIYAKU CO LTD | 1984-02-01 | — | — | JP | disclosed |
| JP-S05920256-A | — | — | 0001-01-01 | — | — | JP | disclosed |