Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.60 |
| ▸ | MEN1 | O00255 | 5/20 | 0.60 |
| ▸ | MGLL | Q99685 | 1/20 | 0.53 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.46 |
| ▸ | CASP6 | P55212 | 3/20 | 0.45 |
| ▸ | CASP3 | P42574 | 2/20 | 0.45 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.45 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.45 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | PGR | P06401 | 1/20 | 0.40 |
| ▸ | TNKS | O95271 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11032644 | 0.86 | HPGD (0.59) | HPGDKMT2AMEN1MGLLNOTUM | |
| SCHEMBL30143567 | 0.82 | KMT2A (0.50) | HPGDKMT2AMEN1MGLLNOTUM | |
| SCHEMBL25313932 | 0.81 | HPGD (0.50) | HPGDKMT2AMEN1MGLLNOTUM | |
| SCHEMBL6765903 | 0.79 | HPGD (0.74) | HPGDKMT2AMEN1MGLLNOTUM | |
| SCHEMBL11133610 | 0.78 | HPGD (0.62) | HPGDKMT2AMEN1MGLLNOTUM | |
| SCHEMBL143970 | 0.77 | HPGD (1.00) | HPGDKMT2AMEN1NOTUMCASP6 | |
| SCHEMBL31422646 | 0.77 | HPGD (1.00) | HPGDKMT2AMEN1NOTUMCASP6 | |
| SCHEMBL28494976 | 0.76 | KMT2A (0.58) | HPGDKMT2AMEN1MGLLCASP6 | |
| SCHEMBL28933339 | 0.76 | KMT2A (0.61) | HPGDKMT2AMEN1MGLLEPHX2 | |
| SCHEMBL25315877 | 0.76 | HPGD (0.44) | HPGDKMT2AMEN1NOTUMCASP6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1349852-A2 | 4-(HETERO)ARYL SUBSTITUTED INDOLINONES | Sugen, Inc. (US) | 2003-10-08 | — | — | EP | claimed |
| WO-2002055517-A2 | 4-(HETERO)ARYL SUBSTITUTED INDOLINONES | CUI JINGRONG (US) | 2002-07-18 | — | — | WO | claimed |