Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CASP7 | P55210 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1906009 | 0.90 | LMNA (0.33) | — | |
| SCHEMBL10351408 | 0.79 | GAA (0.32) | ALDH1A1TSHR | |
| SCHEMBL11029817 | 0.67 | — | — | |
| SCHEMBL12705714 | 0.62 | LMNA (0.73) | ALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL8573161 | 0.59 | ALDH1A1 (0.35) | ALDH1A1TSHRMAPK1CASP7SMN1; SMN2 | |
| SCHEMBL11027249 | 0.58 | LMNA (0.39) | — | |
| SCHEMBL14365467 | 0.56 | LMNA (0.37) | ALDH1A1TSHRMAPK1CASP7SMN1; SMN2 | |
| SCHEMBL10111182 | 0.56 | LMNA (0.62) | ALDH1A1TSHRMAPK1CASP7SMN1; SMN2 | |
| SCHEMBL11029202 | 0.53 | LMNA (0.33) | TSHR | |
| SCHEMBL14557562 | 0.53 | ALDH1A1 (0.33) | ALDH1A1TSHRMAPK1CASP7SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0078784-B1 | THIO-SUBSTITUTED-1,3,5-TRIAZINE-DIAMINES AND -TRIAMINES USEFUL AS PREVULCANIZATION INHIBITORS | MONSANTO COMPANY (US) | 1985-07-03 | — | — | EP | disclosed |
| US-4460769-A | Thio-amino-1,3,5-triazines | MONSANTO COMPANY (US) | 1984-07-17 | — | — | US | disclosed |
| EP-0078784-A1 | Thio-substituted-1,3,5-triazine-diamines and -triamines useful as prevulcanization inhibitors | MONSANTO COMPANY (US) | 1983-05-11 | — | — | EP | disclosed |
| US-4380609-A | Prevulcanization inhibitors of thio-triazine-amines for rubber | MONSANTO COMPANY (US) | 1983-04-19 | — | — | US | disclosed |