SCHEMBL11032772

SCHEMBL11032772

O=C1Cc2ccccc2N=C1S(=O)(=O)O

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BCHE P06276 1/20 0.40
CES1 P23141 1/20 0.40
NOS3 P29474 1/20 0.38
NOS1 P29475 1/20 0.38
NOS2 P35228 1/20 0.38
HRH4 Q9H3N8 1/20 0.36
MAOA P21397 2/20 0.34
PDE3B Q13370 1/20 0.34
PDE3A Q14432 1/20 0.34
ALDH1A1 P00352 5/20 0.33
CYP1A2 P05177 2/20 0.33
KDM4E B2RXH2 2/20 0.33
HPGD P15428 2/20 0.33
TRPA1 O75762 2/20 0.33
MAOB P27338 1/20 0.33
SIGMAR1 Q99720 1/20 0.33
TSHR P16473 2/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
HRH1 P35367 2/20 0.32
HTR2A P28223 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31386660 0.77 NOS3 (0.41) BCHENOS3NOS1NOS2HRH4
SCHEMBL9958235 0.76 BCHE (0.37) BCHECES1NOS3NOS1NOS2
SCHEMBL4145325 0.74 NOS3 (0.42) BCHECES1NOS3NOS1NOS2
SCHEMBL9674946 0.71 NOS3 (0.42) BCHECES1NOS3NOS1NOS2
SCHEMBL8177168 0.71 NOS3 (0.42) BCHECES1NOS3NOS1NOS2
SCHEMBL3626217 0.71 NOS3 (0.52) BCHECES1NOS3NOS1NOS2
SCHEMBL5841961 0.70 NOS3 (0.39) BCHECES1NOS3NOS1NOS2
SCHEMBL2866347 0.70 MAOA (0.45) BCHECES1NOS3NOS1NOS2
SCHEMBL729365 0.69 NOS3 (0.41) BCHECES1NOS3NOS1NOS2
SCHEMBL8980495 0.68 IDO1 (0.42) BCHECES1NOS3NOS1NOS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4617382-A PRINTING; DYEING; SILK, LEATHER, WOOL AND POLYAMIDES CIBA-GEIGY CORPORATION (US) 1986-10-14 US disclosed