Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 6/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | RARA | P10276 | 1/20 | 0.41 |
| ▸ | RARB | P10826 | 1/20 | 0.41 |
| ▸ | RXRA | P19793 | 1/20 | 0.41 |
| ▸ | RXRB | P28702 | 1/20 | 0.41 |
| ▸ | RXRG | P48443 | 1/20 | 0.41 |
| ▸ | NOS3 | P29474 | 1/20 | 0.40 |
| ▸ | NOS1 | P29475 | 1/20 | 0.40 |
| ▸ | NOS2 | P35228 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | CES1 | P23141 | 1/20 | 0.38 |
| ▸ | CFTR | P13569 | 1/20 | 0.36 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14507199 | 0.78 | IDO1 (0.50) | IDO1MAPTLMNAGAARARA | |
| SCHEMBL28634257 | 0.77 | LMNA (0.39) | MAPTLMNAGAABCHEKMT2A | |
| SCHEMBL3443792 | 0.76 | KDM4E (0.41) | MAPTLMNANOS3NOS1NOS2 | |
| SCHEMBL15066599 | 0.76 | BCHE (0.42) | MAPTLMNARARARARBRXRA | |
| SCHEMBL16243903 | 0.75 | MEN1 (0.40) | MAPTLMNARARARARBRXRA | |
| SCHEMBL3626217 | 0.73 | NOS3 (0.52) | MAPTNOS3NOS1NOS2ALDH1A1 | |
| SCHEMBL9674946 | 0.73 | NOS3 (0.42) | MAPTLMNANOS3NOS1NOS2 | |
| SCHEMBL8177168 | 0.73 | NOS3 (0.42) | MAPTLMNAGAANOS3NOS1 | |
| SCHEMBL4145325 | 0.73 | NOS3 (0.42) | MAPTLMNANOS3NOS1NOS2 | |
| SCHEMBL2866347 | 0.73 | MAOA (0.45) | MAPTRARARARBRXRARXRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103391932-B | For suppressing the heterogeneous ring compound of PASK | BIOENERGENIX (US) | 2015-10-14 | — | — | CN | disclosed |
| CN-103391932-A | Heterocyclic compounds for the inhibition of pask | BIOENERGENIX | 2013-11-13 | — | — | CN | disclosed |
| US-5571822-A | AMINO-2-PHENYL-4-QUINOLONE DERIVATIVES | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 1996-11-05 | — | — | US | disclosed |
| WO-1996010563-A1 | 2-ARYL-4-QUINOLONES AS ANTITUMOR COMPOUNDS | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 1996-04-11 | — | — | WO | disclosed |