Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | TRPA1 | O75762 | 4/20 | 0.41 |
| ▸ | NOS3 | P29474 | 1/20 | 0.39 |
| ▸ | NOS1 | P29475 | 1/20 | 0.39 |
| ▸ | NOS2 | P35228 | 1/20 | 0.39 |
| ▸ | RARA | P10276 | 1/20 | 0.38 |
| ▸ | RARB | P10826 | 1/20 | 0.38 |
| ▸ | RXRA | P19793 | 1/20 | 0.38 |
| ▸ | RXRB | P28702 | 1/20 | 0.38 |
| ▸ | RXRG | P48443 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | CES1 | P23141 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | HRH1 | P35367 | 3/20 | 0.35 |
| ▸ | HTR2A | P28223 | 2/20 | 0.35 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.35 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11040814 | 0.91 | MAOA (0.39) | MAOAMAOBTRPA1NOS3NOS1 | |
| SCHEMBL7568554 | 0.83 | TRPA1 (0.38) | MAOAMAOBTRPA1NOS3NOS1 | |
| SCHEMBL11036381 | 0.83 | NOS3 (0.37) | MAOAMAOBTRPA1NOS3NOS1 | |
| Potassium Ion SCHEMBL10910684 | 0.83 | NOS3 (0.37) | MAOAMAOBTRPA1NOS3NOS1 | |
| SCHEMBL73322 | 0.83 | NOS3 (0.37) | MAOAMAOBTRPA1NOS3NOS1 | |
| SCHEMBL2783069 | 0.81 | NOS3 (0.36) | MAOAMAOBTRPA1NOS3NOS1 | |
| SCHEMBL2778638 | 0.80 | TRPA1 (0.48) | TRPA1NOS3NOS1NOS2POLB | |
| Hydrochloric Acid SCHEMBL11091871 | 0.78 | NOS3 (0.40) | MAOAMAOBTRPA1NOS3NOS1 | |
| SCHEMBL515808 | 0.76 | TRPA1 (0.44) | MAOAMAOBTRPA1NOS3NOS1 | |
| SCHEMBL29697828 | 0.76 | TRPA1 (0.44) | MAOAMAOBTRPA1NOS3NOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 94 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2059124-B1 | POLYMERIC SURFACTANT USEFUL FOR THE PREPARATION OF PESTICIDAL AGROCHEMICAL COMPOSITIONS | LAMBERTI SPA (IT) | 2016-06-15 | — | — | EP | claimed |
| US-6897315-B2 | Method for producing 8-methoxy-quinolinecarboxylic acids | BAYER HEALTHCARE AKTIENGESELLSCHAFT (DE) | 2005-05-24 | — | — | US | claimed |
| EP-1034173-B1 | METHOD FOR PRODUCING 8-METHOXY-QUINOLINE CARBOXYLIC ACIDS | BAYER HEALTHCARE AG (DE) | 2005-04-27 | — | — | EP | claimed |
| US-20030208069-A1 | Method for producing 8-methoxy-quinoline carboxylic acids | BAYER AKTIENGESELLSCHAFT (DE) | 2003-11-06 | — | — | US | claimed |
| US-20030139454-A1 | Fungicidal active compound combinations | STENZEL KLAUS (DE) | 2003-07-24 | — | — | US | claimed |
| US-20010016591-A1 | Fungicidal active compound combinations | STENZEL KLAUS (DE) | 2001-08-23 | — | — | US | claimed |
| EP-0707792-B1 | Fungicidal combinations of active agents | BAYER AG (DE) | 1999-01-20 | — | — | EP | claimed |
| EP-0657448-B1 | One pot process for the preparation of 3-quinolonecarboxylic acid derivatives | BAYER AG (DE) | 1998-03-04 | — | — | EP | claimed |
| US-5639886-A | One-pot process for the preparation of 3-quinolonecarboxylic acid derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 1997-06-17 | — | — | US | claimed |
| EP-0233910-B1 | PLANT PROTECTING COMPOSITION | INNOFINANCE Altalános Innovácios Pénzintézet (HU) | 1990-09-19 | — | — | EP | claimed |
| EP-0188194-B1 | AMINOACRYLIC ACID DERIVATIVES | BAYER AG (DE) | 1990-07-04 | — | — | EP | claimed |
| EP-0149560-B1 | FUNGICIDAL COMPOSITIONS | UNIROYAL LIMITED (GB) | 1989-12-06 | — | — | EP | claimed |
| CN-86100221-A | AMINOACRYLIC ACID DERIVATIVES | — | 1986-07-16 | — | — | CN | claimed |
| US-4431553-A | Lubricant composition containing metal oxyquinolinate | AUTOIPARI KUTATO INTEZET (HU) | 1984-02-14 | — | — | US | claimed |
| JP-2231476-A | — | — | None | — | — | JP | disclosed |
| JP-7196621-A | — | — | None | — | — | JP | disclosed |
| CN-114128971-B | Hair treatment device and cosmetic method | 欧莱雅 | 2024-04-12 | — | — | CN | disclosed |
| US-4374138-A | PENICILLINS | WARNER-LAMBERT COMPANY (US) | 1983-02-15 | — | — | US | disclosed |
| US-4328341-A | Process for preparing certain pyrano[3,2-g]quinoline 2,8-dicarboxylates and 4-oxo-quinoline-2-carboxylates | FISONS LIMITED (GB) | 1982-05-04 | — | — | US | disclosed |
| EP-0030423-A1 | A process for the production of 1,4-dihydro-4-oxo-quinoline-2-carboxylic acids, or salts, esters or amides thereof and intermediates therefor | FISONS plc (GB) | 1981-06-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030208069-A1 | Method for producing 8-methoxy-quinoline carboxylic acids | QARS1, QPCT, PAM | MAOA 248/4885MAOB 588/4885TRPA1 4487/4885 |
| US-20010016591-A1 | Fungicidal active compound combinations | CYP51A1, ERG28, CYP4X1 | MAOA 1096/4885MAOB 1516/4885TRPA1 1684/4885 |
| US-20030139454-A1 | Fungicidal active compound combinations | CYP51A1, ERG28, CYP4X1 | MAOA 1096/4885MAOB 1516/4885TRPA1 1684/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.