SCHEMBL11033099

SCHEMBL11033099

CNCCN(C)OC(=O)c1ccc(C(=O)ON(C)CCNC)cc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.42
MAPK1 P28482 2/20 0.42
CYP1A2 P05177 1/20 0.42
MAOA P21397 1/20 0.42
CNR1 P21554 1/20 0.42
DRD4 P21917 1/20 0.42
ACHE P22303 1/20 0.42
HRH2 P25021 1/20 0.42
HTR2A P28223 1/20 0.42
HTR2C P28335 1/20 0.42
NTSR1 P30989 1/20 0.42
HRH1 P35367 1/20 0.42
DRD3 P35462 1/20 0.42
SCN1A P35498 1/20 0.42
HTR2B P41595 1/20 0.42
SCN7A Q01118 1/20 0.42
SLC6A3 Q01959 1/20 0.42
KCNH2 Q12809 1/20 0.42
SCN5A Q14524 1/20 0.42
SCN9A Q15858 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21673638 0.91 TSHR (0.48) LMNACYP1A2SCN1ASLC6A3SCN5A
SCHEMBL24218583 0.76 KDM4E (0.50) LMNAMAPK1RAB9AKDM4ENPC1
SCHEMBL829692 0.74 PRMT3 (0.44) PRMT1ALDH1A1MEN1KMT2APRMT3
SCHEMBL3036189 0.74 PRMT1 (0.52) LMNAMAPK1ACHESIGMAR1RAB9A
SCHEMBL5678485 0.73 LMNA (0.53) LMNAMAPK1CYP1A2SCN1ASLC6A3
SCHEMBL144324 0.72 PRMT3 (0.42) PRMT1MEN1KMT2APRMT3CARM1
SCHEMBL26179407 0.72 SMN1; SMN2 (0.39) LMNAMAPK1SCN1ASLC6A3SCN5A
SCHEMBL26179405 0.71 TSHR (0.46) LMNAMAPK1CYP1A2SLC6A3POLB
SCHEMBL4854177 0.71 CA1 (0.44) RAB9APHLPP2MAPTCA1CA2
SCHEMBL19935331 0.70 LMNA (0.50) LMNAMAPK1CYP1A2MAOACNR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0039155-B1 POLYESTER MOLDING COMPOSITION, PRODUCTION THEREOF AND MOLDED ARTICLES PRODUCED THEREFROM Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1985-10-09 EP disclosed
US-4417021-A POLYAMIDES, POLYHYDRAZIDES AS NUCLEATION AGENTS, MOLDING ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1983-11-22 US disclosed
EP-0039155-A1 Polyester molding composition, production thereof and molded articles produced therefrom Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1981-11-04 EP disclosed