SCHEMBL829692

SCHEMBL829692

CNCCN(C)OC(C)=O

nearest known ligand 0.44

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
PRMT3 O60678 1/20 0.44
CARM1 Q86X55 1/20 0.44
PRMT6 Q96LA8 1/20 0.44
PRMT1 Q99873 1/20 0.44
PRMT8 Q9NR22 1/20 0.44
ALDH1A1 P00352 1/20 0.33
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31
KDM4A O75164 1/20 0.31
KDM4C Q9H3R0 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL144324 0.80 PRMT3 (0.42) PRMT3CARM1PRMT6PRMT1PRMT8
SCHEMBL5183458 0.75 PRMT3 (0.38) PRMT3CARM1PRMT6PRMT1PRMT8
SCHEMBL3002127 0.74
SCHEMBL11033099 0.74 LMNA (0.42) PRMT3CARM1PRMT6PRMT1PRMT8
SCHEMBL28935992 0.73 ALDH1A1 (0.38) ALDH1A1KDM4AKDM4C
SCHEMBL179678 0.71
Acetic Acid SCHEMBL14782437 0.71 PRMT3 (0.70) PRMT3CARM1PRMT6PRMT1PRMT8
SCHEMBL8781867 0.71 ALDH1A1 (0.41) ALDH1A1KDM4C
SCHEMBL11838143 0.70
SCHEMBL21673638 0.70 TSHR (0.48) CARM1PRMT6PRMT1ALDH1A1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9957549-B2 Compositions and methods for negative selection of non-desired nucleic acid sequences NUGEN TECHNOLOGIES, INC. (US) 2018-05-01 US disclosed
EP-2861787-B1 COMPOSITIONS AND METHODS FOR NEGATIVE SELECTION OF NON-DESIRED NUCLEIC ACID SEQUENCES NUGEN TECH INC (US) 2017-09-20 EP disclosed
CN-104619894-B Compositions and methods for negative selection of undesired nucleic acid sequences 纽亘技术公司 2017-06-06 CN disclosed
US-20160362680-A1 COMPOSITIONS AND METHODS FOR NEGATIVE SELECTION OF NON-DESIRED NUCLEIC ACID SEQUENCES NUGEN TECHNOLOGIES, INC. 2016-12-15 US disclosed
US-20150299767-A1 COMPOSITIONS AND METHODS FOR NEGATIVE SELECTION OF NON-DESIRED NUCLEIC ACID SEQUENCES NUGEN TECHNOLOGIES, INC. 2015-10-22 US disclosed
EP-2861787-A2 COMPOSITIONS AND METHODS FOR NEGATIVE SELECTION OF NON-DESIRED NUCLEIC ACID SEQUENCES Nugen Technologies, Inc. (US) 2015-04-22 EP disclosed
US-20140065692-A1 Methods for Fragmentation and Labeling of Nucleic Acids NUGEN TECHNOLOGIES INC (US) 2014-03-06 US disclosed
WO-2013191775-A2 COMPOSITIONS AND METHODS FOR NEGATIVE SELECTION OF NON-DESIRED NUCLEIC ACID SEQUENCES NUGEN TECHNOLOGIES, INC. (US) 2013-12-27 WO disclosed
US-8551709-B2 Methods for fragmentation and labeling of nucleic acids NUGEN TECHNOLOGIES, INC. (US) 2013-10-08 US disclosed
WO-2013040094-A1 METHODS AND APPARATUS FOR CARBON DIOXIDE CAPTURE E. I. DU PONT DE NEMOURS AND COMPANY (US) 2013-03-21 WO disclosed
EP-2464738-A1 METHODS, COMPOSITIONS, AND KITS FOR GENERATING NUCLEIC ACID PRODUCTS SUBSTANTIALLY FREE OF TEMPLATE NUCLEIC ACID Nugen Technologies, Inc. (US) 2012-06-20 EP disclosed
US-8143001-B2 Methods for analysis of nucleic acid methylation status and methods for fragmentation, labeling and immobilization of nucleic acids NUGEN TECHNOLOGIES, INC. (US) 2012-03-27 US disclosed
US-20110224105-A1 METHODS, COMPOSITIONS, AND KITS FOR GENERATING NUCLEIC ACID PRODUCTS SUBSTANTIALLY FREE OF TEMPLATE NUCLEIC ACID NUGEN TECHNOLOGIES, INC. (US) 2011-09-15 US disclosed
WO-2011019964-A9 METHODS, COMPOSITIONS, AND KITS FOR GENERATING NUCLEIC ACID PRODUCTS SUBSTANTIALLY FREE OF TEMPLATE NUCLEIC ACID NUGEN TECHNOLOGIES, INC. (US) 2011-08-04 WO disclosed
WO-2011019964-A1 METHODS, COMPOSITIONS, AND KITS FOR GENERATING NUCLEIC ACID PRODUCTS SUBSTANTIALLY FREE OF TEMPLATE NUCLEIC ACID NUGEN TECHNOLOGIES, INC. (US) 2011-02-17 WO disclosed
US-20100022403-A1 METHODS FOR FRAGMENTATION AND LABELING OF NUCLEIC ACIDS KURN NURITH 2010-01-28 US disclosed
US-20090233804-A1 METHODS FOR ANALYSIS OF NUCLEIC ACID METHYLATION STATUS AND METHODS FOR FRAGMENTATION, LABELING AND IMMOBILIZATION OF NUCLEIC ACIDS NUGEN TECHNOLOGIES, INC. 2009-09-17 US disclosed
US-20050208538-A1 Methods for analysis of nucleic acid methylation status and methods for fragmentation, labeling and immobilization of nucleic acids NUGEN TECHNOLOGIES, INC. 2005-09-22 US disclosed
US-20040005614-A1 Methods for fragmentation, labeling and immobilization of nucleic acids NUGEN TECHNOLOGIES, INC. 2004-01-08 US disclosed
US-4672136-A Monoadduct monomers and polyadduct polymers from divinyl ketones THE DOW CHEMICAL COMPANY (US) 1987-06-09 US disclosed