SCHEMBL1103350

SCHEMBL1103350

CN1c2ccccc2CCc2ccc(-c3c4ccccc4c(-c4ccc5c(c4)N(C)c4ccccc4CC5)c4c3cnc3ccccc34)cc21

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP11B1 P15538 2/20 0.34
CYP11B2 P19099 2/20 0.34
MET P08581 2/20 0.32
HSD17B3 P37058 1/20 0.31
LMNA P02545 3/20 0.31
HTT P42858 2/20 0.31
PDPK1 O15530 1/20 0.31
KDM4E B2RXH2 1/20 0.31
MAPT P10636 1/20 0.31
KMT2A Q03164 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31
CYP17A1 P05093 1/20 0.31
CYP1A2 P05177 1/20 0.31
CYP19A1 P11511 1/20 0.31
CDK4 P11802 1/20 0.31
CCND1 P24385 1/20 0.31
TLR7 Q9NYK1 1/20 0.30
TP53 P04637 1/20 0.30
ACVR1 Q04771 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1103352 0.84 ADRA2A (0.32) HSD17B3LMNAHTTKDM4EMAPT
SCHEMBL1103351 0.81 PDPK1 (0.34) LMNAHTTPDPK1KDM4EMAPT
SCHEMBL1102571 0.79 CYP11B1 (0.40) CYP11B1CYP11B2HSD17B3CYP17A1CYP1A2
SCHEMBL1102964 0.78 KMT2A (0.36) CYP11B1CYP11B2HSD17B3LMNAHTT
SCHEMBL1103278 0.77 CYP11B1 (0.41) CYP11B1CYP11B2LMNAHTTPDPK1
SCHEMBL1103555 0.76 MET (0.39) CYP11B1CYP11B2METLMNAHTT
SCHEMBL1103349 0.74 ADORA3 (0.34) LMNAPDPK1KDM4EMAPTCDK4
SCHEMBL1103442 0.74 TLR7 (0.35) LMNAHTTKDM4EMAPTSMN1; SMN2
SCHEMBL1103331 0.73 GPR3 (0.42) CYP11B2LMNAHTTPDPK1KDM4E
SCHEMBL1103336 0.73 CDK4 (0.39) LMNAHTTPDPK1KDM4EMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8153279-B2 Organic electroluminescent compounds and organic electroluminescent device using the same GRACEL DISPLAY INC. (KR) 2012-04-10 US disclosed
US-8153279-B2 Organic electroluminescent compounds and organic electroluminescent device using the same GRACEL DISPLAY INC. (KR) 2012-04-10 US disclosed
US-20100033083-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same GRACEL DISPLAY INC. (KR) 2010-02-11 US disclosed
US-20100033083-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same GRACEL DISPLAY INC. (KR) 2010-02-11 US disclosed
EP-2147962-A1 Azaanthracene-derivatives and organic electroluminescent device using the same Gracel Display Inc. (KR) 2010-01-27 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100033083-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same ORMDL3, OCIAD2, OCIAD1 CYP11B1 836/4885CYP11B2 652/4885MET 4191/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.