Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 4/20 | 0.68 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.52 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.52 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.49 |
| ▸ | ITGAV | P06756 | 2/20 | 0.49 |
| ▸ | PRMT5 | O14744 | 5/20 | 0.49 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.47 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.47 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.47 |
| ▸ | CDC42 | P60953 | 1/20 | 0.47 |
| ▸ | RAC1 | P63000 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4043277 | 0.88 | HTR2C (0.67) | HTR2CMTNR1AMTNR1BITGB3ITGAV | |
| SCHEMBL3828577 | 0.88 | HTR2C (0.67) | HTR2CMTNR1AMTNR1BITGB3ITGAV | |
| SCHEMBL11032483 | 0.81 | HTR2C (0.65) | HTR2CPRMT5HDAC8HDAC6CYP1A2 | |
| SCHEMBL4042962 | 0.81 | HTR2C (0.65) | HTR2CPRMT5HDAC8HDAC6HTR2A | |
| SCHEMBL4042963 | 0.81 | HTR2C (0.65) | HTR2CPRMT5HDAC8HDAC6HTR2A | |
| SCHEMBL30839291 | 0.79 | HTR2C (0.73) | HTR2CMTNR1AMTNR1BPRMT5HDAC11 | |
| SCHEMBL29162348 | 0.79 | HTR2C (0.73) | HTR2CMTNR1AMTNR1BPRMT5HDAC11 | |
| SCHEMBL25521336 | 0.79 | HTR2C (0.73) | HTR2CMTNR1AMTNR1BPRMT5HDAC11 | |
| SCHEMBL14876186 | 0.79 | MTNR1A (0.58) | HTR2CMTNR1AMTNR1BHDAC11HDAC8 | |
| SCHEMBL22930056 | 0.78 | HTR2C (0.77) | HTR2CMTNR1AMTNR1BPRMT5HDAC11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4448785-A | N-Unsaturated fatty acid amides of tryptophan ester homologues and anti-cholesteric use thereof | SANDOZ, INC. (US) | 1984-05-15 | — | — | US | disclosed |