Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL32680041 | 0.74 | POLB (0.47) | SMN1; SMN2ALDH1A1 | |
| SCHEMBL29653558 | 0.72 | — | — | |
| SCHEMBL30988452 | 0.69 | MAP3K5 (0.42) | — | |
| SCHEMBL20472009 | 0.66 | ASIC3 (0.37) | RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL7205591 | 0.62 | — | — | |
| SCHEMBL5779690 | 0.62 | — | — | |
| SCHEMBL8763485 | 0.61 | ADORA2B (0.32) | — | |
| SCHEMBL18912024 | 0.61 | IRAK4 (0.34) | RAB9AALDH1A1 | |
| SCHEMBL4607798 | 0.61 | SMN1; SMN2 (0.51) | SMN1; SMN2ALDH1A1 | |
| SCHEMBL27364397 | 0.60 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4497814-A | 2-(Pyridinyl)-1,2,4-triazolo[1,5-a]pyrimidines and derivatives useful in increasing cardiac contractility | SCHERING CORPORATION (US) | 1985-02-05 | — | — | US | disclosed |