Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 8/20 | 0.47 |
| ▸ | RAB9A | P51151 | 7/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | POLB | P06746 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | CES2 | O00748 | 1/20 | 0.47 |
| ▸ | CES1 | P23141 | 1/20 | 0.47 |
| ▸ | DAO | P14920 | 1/20 | 0.46 |
| ▸ | GSK3B | P49841 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.41 |
| ▸ | FEN1 | P39748 | 1/20 | 0.41 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6391388 | 0.74 | NPC1 (0.42) | NPC1RAB9AALDH1A1POLBMEN1 | |
| SCHEMBL758450 | 0.73 | ALDH1A1 (0.62) | NPC1RAB9AALDH1A1POLBMEN1 | |
| SCHEMBL4879913 | 0.72 | CYP3A4 (0.56) | NPC1RAB9AALDH1A1POLBMEN1 | |
| SCHEMBL13843775 | 0.71 | — | — | |
| SCHEMBL299822 | 0.71 | AKT1 (0.47) | ALDH1A1POLBMEN1KMT2ALMNA | |
| SCHEMBL6378691 | 0.70 | — | — | |
| SCHEMBL1263271 | 0.70 | — | — | |
| SCHEMBL11290367 | 0.69 | CES2 (0.52) | NPC1RAB9AALDH1A1POLBMEN1 | |
| SCHEMBL10982372 | 0.69 | DAO (0.55) | NPC1RAB9AALDH1A1POLBMEN1 | |
| SCHEMBL1520699 | 0.69 | KDM4E (0.62) | NPC1RAB9AALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4496560-A | ACTIVE AGAINST GRAMPOSITIVE BACTERIA | RHONE-POULENC SANTE (FR) | 1985-01-29 | — | — | US | claimed |