Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | MC4R | P32245 | 1/20 | 0.35 |
| ▸ | SCN4A | P35499 | 1/20 | 0.35 |
| ▸ | MC3R | P41968 | 1/20 | 0.35 |
| ▸ | HTR3A | P46098 | 1/20 | 0.35 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11671374 | 0.82 | CYP3A4 (0.38) | LMNACYP3A4NPSR1ALDH1A1KDM4E | |
| SCHEMBL10992754 | 0.80 | LMNA (0.40) | LMNACYP3A4ALDH1A1KDM4ETSHR | |
| SCHEMBL8942110 | 0.80 | ALDH1A1 (0.44) | LMNACYP3A4ALDH1A1TSHRMEN1 | |
| SCHEMBL11308268 | 0.79 | KCNH2 (0.36) | KDM4ETSHRKMT2AKCNH2 | |
| SCHEMBL10766412 | 0.79 | CYP3A4 (0.37) | LMNACYP3A4NPSR1ALDH1A1KDM4E | |
| SCHEMBL11673976 | 0.76 | LMNA (0.36) | LMNACYP3A4ALDH1A1TSHRTRPM8 | |
| SCHEMBL11389447 | 0.75 | LMNA (0.42) | LMNACYP3A4NPSR1ALDH1A1KDM4E | |
| SCHEMBL20467009 | 0.75 | CYP3A4 (0.41) | LMNACYP3A4NPSR1ALDH1A1TSHR | |
| SCHEMBL10973330 | 0.74 | MAPT (0.42) | LMNANPSR1ALDH1A1KDM4EMEN1 | |
| SCHEMBL11670972 | 0.73 | ALDH1A1 (0.37) | LMNACYP3A4ALDH1A1TSHRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4500715-A | CHEMICAL INTERMEDIATES FOR PLANT SAFENING AGENTS AND DYES | BAYER AKTIENGESELLSCHAFT (DE) | 1985-02-19 | — | — | US | disclosed |
| US-4268438-A | Cationic 1,3,4-thiadiazole dyestuffs | BAYER AKTIENGESELLSCHAFT (DE) | 1981-05-19 | — | — | US | disclosed |