Trolamine

Trolamine

SCHEMBL11034528

CC(C)(N)CO.CN(C)CCO.OCCN(CCO)CCO

nearest known ligand 0.55

Full drug profile on Sugi Atlas →

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.55
KDM4E B2RXH2 1/20 0.32
ALDH1A1 P00352 1/20 0.32
HPGD P15428 1/20 0.32
MAPK1 P28482 1/20 0.32
HTT P42858 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
HTR1A P08908 1/20 0.30
DRD2 P14416 1/20 0.30
HTR2A P28223 1/20 0.30
HTR7 P34969 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Deanol SCHEMBL7163532 0.93 MAPT (0.63) MAPTALDH1A1HTR1ADRD2HTR2A
Trolamine SCHEMBL4518758 0.91 MAPT (0.36) MAPTKDM4EALDH1A1HPGDMAPK1
Trolamine SCHEMBL15410677 0.83 MAPT (0.80) MAPTKDM4EALDH1A1HPGDMAPK1
Trolamine SCHEMBL11034532 0.81 MAPT (0.32) MAPT
Trolamine SCHEMBL11034525 0.80 KDM4E (0.31) MAPTKDM4EALDH1A1HPGDMAPK1
Deanol SCHEMBL2059818 0.79 CYP1A2 (0.47) MAPTKDM4EALDH1A1HPGDMAPK1
Diethylaminoethanol SCHEMBL10476578 0.79 CYP1A2 (0.42) MAPTKDM4EALDH1A1HPGDMAPK1
Trolamine SCHEMBL28044314 0.77 MAPT (0.69) MAPTKDM4EALDH1A1HPGDMAPK1
SCHEMBL5014917 0.76 ARG1 (0.36) MAPTKDM4EALDH1A1HPGDMAPK1
SCHEMBL5965815 0.76 ARG1 (0.36) MAPTKDM4EALDH1A1HPGDMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0045143-B1 ALKALI-SOLUBLE HOT MELT ADHESIVE COMPOSITIONS Gulf Oil Corporation (US) 1984-10-24 EP disclosed