Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 2/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | MMP1 | P03956 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | MMP9 | P14780 | 1/20 | 0.38 |
| ▸ | MMP8 | P22894 | 1/20 | 0.38 |
| ▸ | MMP13 | P45452 | 1/20 | 0.38 |
| ▸ | RAPGEF4 | Q8WZA2 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | F2 | P00734 | 1/20 | 0.34 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3530399 | 1.00 | SLC6A2 (0.39) | SLC6A2SLC6A4SLC6A3CA1CA2 | |
| SCHEMBL21753734 | 0.84 | ALDH1A1 (0.50) | SLC6A2SLC6A4SLC6A3CA1RAPGEF4 | |
| SCHEMBL9686493 | 0.80 | SLC6A2 (0.40) | SLC6A2SLC6A4SLC6A3CA1CA2 | |
| SCHEMBL18287890 | 0.80 | IGFBP3 (0.41) | SLC6A2SLC6A4SLC6A3CA1CA2 | |
| SCHEMBL23495805 | 0.79 | MEN1 (0.40) | CA1RAPGEF4 | |
| SCHEMBL13021426 | 0.79 | SLC6A2 (0.44) | SLC6A2SLC6A4SLC6A3CA1CA2 | |
| SCHEMBL19126691 | 0.79 | GABRA1 (0.39) | RAPGEF4ALDH1A1LMNA | |
| SCHEMBL6055138 | 0.79 | SLC6A2 (0.44) | SLC6A2SLC6A4SLC6A3CA1CA2 | |
| SCHEMBL13021424 | 0.79 | SLC6A2 (0.44) | SLC6A2SLC6A4SLC6A3CA1CA2 | |
| Hydrogen Peroxide SCHEMBL10882706 | 0.78 | LDHA (0.39) | SLC6A2SLC6A4SLC6A3CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0161580-A2 | Process for the preparation of a lacton | F. HOFFMANN-LA ROCHE AG (CH) | 1985-11-21 | — | — | EP | disclosed |