SCHEMBL11035644

SCHEMBL11035644

CCc1ccccc1-c1cc(=O)c2ccccc2o1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 7/20 0.63
NPC1 O15118 6/20 0.63
RAB9A P51151 6/20 0.63
SMN1; SMN2 Q16637 6/20 0.63
AKR1C3 P42330 1/20 0.63
AKR1C2 P52895 1/20 0.63
AKR1C1 Q04828 1/20 0.63
CYP3A4 P08684 5/20 0.58
KDM4E B2RXH2 5/20 0.58
TP53 P04637 4/20 0.58
MAPT P10636 4/20 0.58
MEN1 O00255 3/20 0.58
CYP2C9 P11712 3/20 0.58
CYP2C19 P33261 3/20 0.58
KMT2A Q03164 3/20 0.58
CYP2D6 P10635 2/20 0.58
ALOX15 P16050 2/20 0.58
HSD17B10 Q99714 2/20 0.58
TDP1 Q9NUW8 2/20 0.58
ALOX12 P18054 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10800023 0.86 HPGD (0.55) HPGDNPC1RAB9ASMN1; SMN2AKR1C3
SCHEMBL10800581 0.85 HPGD (0.53) HPGDNPC1RAB9ASMN1; SMN2AKR1C3
SCHEMBL27806529 0.84 HPGD (0.67) HPGDNPC1RAB9ASMN1; SMN2AKR1C3
SCHEMBL29129658 0.82 HPGD (0.61) HPGDNPC1SMN1; SMN2AKR1C3AKR1C2
SCHEMBL623886 0.82 AKR1C3 (0.57) HPGDNPC1RAB9ASMN1; SMN2AKR1C3
SCHEMBL29128894 0.82 AR (0.73) HPGDNPC1RAB9ASMN1; SMN2CYP3A4
SCHEMBL3205778 0.81 HPGD (0.67) HPGDNPC1RAB9ASMN1; SMN2AKR1C3
SCHEMBL27883079 0.80 ALDH1A1 (0.65) HPGDNPC1RAB9ASMN1; SMN2CYP3A4
SCHEMBL8630307 0.80 HPGD (0.55) HPGDNPC1RAB9ASMN1; SMN2AKR1C3
SCHEMBL18015826 0.79 MAOB (0.57) NPC1RAB9ASMN1; SMN2CYP3A4KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 189 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118994185-A 2- (2-Phenethyl) chromone and lignan hybrid and application thereof 中国热带农业科学院热带生物技术研究所 2024-11-22 CN claimed
CN-117821478-A Application of aquilaria sinensis oxymethyl transferase gene AsOMT11 and coded product 中国林业科学研究院林业研究所 2024-04-05 CN claimed
CN-117802122-A Application of ASCYP82G1 gene and coded product related to agilawood chromone synthesis 中国林业科学研究院林业研究所 2024-04-02 CN claimed
CN-114949081-B Preparation method and application of agilawood extract for resisting helicobacter pylori 海南娜古芳沉香科技有限公司 2024-01-26 CN claimed
CN-117269395-A Construction method of qi fingerprint of agilawood and fingerprint thereof 中国中医科学院中药研究所 2023-12-22 CN claimed
CN-115581642-B Body lotion with antibacterial effect and preparation method and application thereof 旸森生态科技有限公司 2023-12-22 CN claimed
CN-113264912-B Method for extracting 2- (2-phenethyl) chromone component from agilawood and application thereof 中国热带农业科学院热带生物技术研究所 2023-07-04 CN claimed
CN-112772962-B Cut tobacco and cigarette containing aquilaria sinensis extract and preparation method thereof 海南黎药堂生物科技开发有限公司 2023-05-23 CN claimed
CN-116041465-A Aquilaria sinensis chromone synthesis related MYB transcription inhibitor AsMYB4 and application thereof 中国热带农业科学院热带生物技术研究所 2023-05-02 CN claimed
CN-112806605-B Preparation method of kannan agilawood-flavor cigar tobacco leaves and cigar 海南贵本南药科技有限公司 2023-03-10 CN claimed
CN-114487199-A Structure analysis method of chromone polymer in agilawood and application thereof 中国热带农业科学院分析测试中心 2022-05-13 CN claimed
CN-108752302-B Application of 2- (2-phenethyl) chromone compound in agilawood 广州大学 2021-09-24 CN claimed
CN-113264912-A Extraction method and application of 2- (2-phenethyl) chromone component in Kyara 中国热带农业科学院热带生物技术研究所 2021-08-17 CN claimed
CN-112772962-A Tobacco shred and cigarette containing aquilaria sinensis extract and preparation method of tobacco shred and cigarette 海南黎药堂生物科技开发有限公司 2021-05-11 CN claimed
CN-107034252-B Method for inducing aquilaria sinensis callus cells to generate 2- (2-phenethyl) chromone components 北京中医药大学 2020-09-11 CN claimed
CN-106290613-B A method of identifying the odd nanmu agalloch eaglewood true and false 中国热带农业科学院热带生物技术研究所 2019-06-07 CN claimed
CN-108752302-A The purposes of 2- (2- phenethyls) chromone compounds in agalloch eaglewood 广州大学 2018-11-06 CN claimed
CN-107034252-A The method that one kind induction suspension culture of Aquilaria sinensis healing cell produces 2- (2- phenethyls) chromone constituents 北京中医药大学 2017-08-11 CN claimed
CN-106290613-A A kind of method identifying the strange nanmu Lignum Aquilariae Resinatum true and false 中国热带农业科学院热带生物技术研究所 2017-01-04 CN claimed
CN-102818782-A Determination method of total 2-(2-phenethyl) chromone compound content INST OF MEDICINAL PLANT DEV CHINESE ACADEMY OF MEDICAL SCIENCES HAINAN BRANCH 2012-12-12 CN claimed