Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 7/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.61 |
| ▸ | MAPT | P10636 | 5/20 | 0.61 |
| ▸ | TP53 | P04637 | 4/20 | 0.61 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.61 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.61 |
| ▸ | CASP7 | P55210 | 2/20 | 0.61 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.61 |
| ▸ | CASP1 | P29466 | 1/20 | 0.61 |
| ▸ | MEN1 | O00255 | 7/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.56 |
| ▸ | POLB | P06746 | 4/20 | 0.56 |
| ▸ | GAA | P10253 | 4/20 | 0.56 |
| ▸ | BLM | P54132 | 4/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.56 |
| ▸ | RECQL | P46063 | 3/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.56 |
| ▸ | USP2 | O75604 | 3/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29129663 | 0.87 | CYP2C19 (0.68) | HPGDKDM4EMAPTTP53ALOX15 | |
| SCHEMBL27806529 | 0.85 | HPGD (0.67) | HPGDKDM4EMAPTTP53ALOX15 | |
| SCHEMBL11035644 | 0.82 | HPGD (0.63) | HPGDKDM4EMAPTTP53ALOX15 | |
| SCHEMBL27883079 | 0.81 | ALDH1A1 (0.65) | HPGDKDM4EMAPTTP53ALOX15 | |
| SCHEMBL6241468 | 0.78 | MEN1 (0.74) | HPGDKDM4EMAPTTP53ALOX15 | |
| SCHEMBL17128869 | 0.78 | ALOX5 (0.45) | HPGDKDM4EMAPTTP53MEN1 | |
| SCHEMBL29128894 | 0.77 | AR (0.73) | HPGDKDM4EMAPTTP53HSD17B10 | |
| Flavanone SCHEMBL980197 | 0.76 | TP53 (1.00) | HPGDKDM4EMAPTTP53ALOX15 | |
| Flavanone SCHEMBL29678059 | 0.76 | TP53 (1.00) | HPGDKDM4EMAPTTP53ALOX15 | |
| SCHEMBL27997244 | 0.75 | MAPT (0.54) | HPGDKDM4EMAPTTP53ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118078802-A | Application of 2- (2-phenethyl) chromone derivative in preparation of medicine for treating lung cancer | 南京上元堂沉香生物科技有限公司 | 2024-05-28 | — | — | CN | disclosed |
| CN-118078802-A | Application of 2- (2-phenethyl) chromone derivative in preparation of medicine for treating lung cancer | 南京上元堂沉香生物科技有限公司 | 2024-05-28 | — | — | CN | disclosed |
| CN-117250298-A | Construction method of liquid fingerprint of agilawood and fingerprint thereof | 中国中医科学院中药研究所 | 2023-12-19 | — | — | CN | disclosed |