Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 5/20 | 0.55 |
| ▸ | NPC1 | O15118 | 5/20 | 0.55 |
| ▸ | RAB9A | P51151 | 4/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.55 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.55 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.55 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | TP53 | P04637 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL623886 | 0.81 | AKR1C3 (0.57) | HPGDNPC1RAB9ASMN1; SMN2AKR1C3 | |
| SCHEMBL11035644 | 0.80 | HPGD (0.63) | HPGDNPC1RAB9ASMN1; SMN2AKR1C3 | |
| SCHEMBL8025501 | 0.74 | HPGD (0.67) | HPGDNPC1RAB9ASMN1; SMN2AKR1C3 | |
| SCHEMBL10800023 | 0.74 | HPGD (0.55) | HPGDNPC1RAB9ASMN1; SMN2AKR1C3 | |
| SCHEMBL10800581 | 0.73 | HPGD (0.53) | HPGDNPC1RAB9ASMN1; SMN2AKR1C3 | |
| SCHEMBL4634256 | 0.72 | HPGD (0.73) | HPGDNPC1RAB9ASMN1; SMN2AKR1C3 | |
| SCHEMBL4634792 | 0.71 | HPGD (0.59) | HPGDNPC1RAB9ASMN1; SMN2AKR1C3 | |
| SCHEMBL25186939 | 0.71 | HPGD (0.67) | HPGDNPC1RAB9ASMN1; SMN2AKR1C3 | |
| SCHEMBL87773 | 0.71 | HPGD (0.67) | HPGDNPC1RAB9ASMN1; SMN2AKR1C3 | |
| SCHEMBL530293 | 0.71 | HPGD (0.67) | HPGDNPC1RAB9ASMN1; SMN2AKR1C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5849786-A | Process for the treatment or prevention of herpes | BIDEL CHRISTIAN-GEORGES (FR) | 1998-12-15 | — | — | US | disclosed |