Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.44 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.44 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | TACR1 | P25103 | 1/20 | 0.40 |
| ▸ | HRH1 | P35367 | 3/20 | 0.40 |
| ▸ | DRD3 | P35462 | 2/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | HRH2 | P25021 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | TEK | Q02763 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11034451 | 0.99 | HPGD (0.46) | OPRM1OPRD1OPRK1KCNA5HPGD | |
| SCHEMBL11035757 | 0.91 | HRH1 (0.48) | OPRM1OPRD1OPRK1KCNA5HPGD | |
| Hydrochloric Acid SCHEMBL11034791 | 0.90 | HRH1 (0.49) | OPRM1OPRD1OPRK1KCNA5HPGD | |
| SCHEMBL11097971 | 0.87 | OPRD1 (0.51) | OPRM1OPRD1OPRK1KCNA5TACR1 | |
| SCHEMBL11034834 | 0.86 | OPRD1 (0.52) | OPRM1OPRD1OPRK1TACR1HTR2A | |
| Hydrochloric Acid SCHEMBL11036480 | 0.86 | OPRD1 (0.50) | OPRM1OPRD1OPRK1KCNA5TACR1 | |
| Hydrochloric Acid SCHEMBL11034648 | 0.85 | OPRD1 (0.51) | OPRM1OPRD1OPRK1TACR1HRH1 | |
| SCHEMBL11034679 | 0.85 | OPRK1 (0.49) | OPRM1OPRD1OPRK1KCNA5HRH1 | |
| SCHEMBL11036099 | 0.82 | DRD2 (0.55) | OPRM1OPRD1OPRK1TACR1HTR2A | |
| SCHEMBL11037592 | 0.80 | OPRD1 (0.52) | OPRM1OPRD1OPRK1KCNA5HRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0048705-B1 | 2-(4-(DIPHENYLMETHYLENE)-1-PIPERIDINYL)-ACETIC ACIDS AND THEIR AMIDES, THEIR PREPARATION AND PHARMACEUTICAL PREPARATIONS CONTAINING THEM | U C B, S.A. (BE) | 1984-07-11 | — | — | EP | claimed |
| EP-0048705-A1 | 2-(4-(Diphenylmethylene)-1-piperidinyl)-acetic acids and their amides, their preparation and pharmaceutical preparations containing them | U C B, S.A. (BE) | 1982-03-31 | — | — | EP | claimed |
| EP-0048705-B1 | 2-(4-(DIPHENYLMETHYLENE)-1-PIPERIDINYL)-ACETIC ACIDS AND THEIR AMIDES, THEIR PREPARATION AND PHARMACEUTICAL PREPARATIONS CONTAINING THEM | U C B, S.A. (BE) | 1984-07-11 | — | — | EP | disclosed |