SCHEMBL6530701

SCHEMBL6530701

C=CC(=O)NCc1cc(Cc2ccccc2)cc(-n2nc3ccccc3n2)c1O

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 2/20 0.39
PTPN2 P17706 1/20 0.39
PTPN6 P29350 1/20 0.39
TGM2 P21980 3/20 0.38
EGFR P00533 1/20 0.38
BTK Q06187 1/20 0.38
NPC1 O15118 1/20 0.35
RAB9A P51151 1/20 0.35
POLB P06746 1/20 0.34
JAK3 P52333 1/20 0.34
ALDH1A1 P00352 3/20 0.33
CYP2C19 P33261 2/20 0.33
TTR P02766 1/20 0.33
BCL2 P10415 1/20 0.33
LMNA P02545 1/20 0.33
CYP2D6 P10635 1/20 0.33
CYP3A4 P08684 1/20 0.33
CYP2C9 P11712 1/20 0.33
MTNR1A P48039 1/20 0.33
MTNR1B P49286 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6530775 0.83 NPC1 (0.51) TGM2EGFRBTKNPC1RAB9A
SCHEMBL27471633 0.83 PTPN1 (0.34) PTPN1PTPN2PTPN6EGFRNPC1
SCHEMBL5339907 0.82 TGM2 (0.40) PTPN1TGM2EGFRBTKNPC1
SCHEMBL5668000 0.81 PTPN1 (0.50) PTPN1PTPN2PTPN6NPC1RAB9A
SCHEMBL11396584 0.80 RAB9A (0.38) TGM2EGFRBTKNPC1RAB9A
SCHEMBL9947193 0.78 EGFR (0.35) EGFRBTKNPC1RAB9APOLB
SCHEMBL9408845 0.78 NPC1 (0.42) PTPN1PTPN2PTPN6NPC1RAB9A
SCHEMBL6511825 0.78 TSHR (0.38) POLBALDH1A1MEN1KMT2A
SCHEMBL13262479 0.77 KDM4E (0.34) EGFRBTKNPC1RAB9APOLB
SCHEMBL5679060 0.77 NPC1 (0.35) TGM2EGFRBTKNPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0834304-B1 Use of liposomogenic UV absorbers to protect hair CIBA SC HOLDING AG (CH) 2005-01-26 EP disclosed
EP-0815071-B1 LIPOSOMOGENIC UV ABSORBERS CIBA SC HOLDING AG (CH) 2001-04-11 EP disclosed
US-6017556-A PROTECTING HUMAN HAIR FROM THE DAMAGING EFFECT OF ULTRAVIOLET RADIATION BY TREATING HUMAN HAIR WITH A LIPOSOMOGENIC ULTRAVIOLET RADIATION ABSORBER CIBA SPECIALTY CHEMICALS CORPORATION (US) 2000-01-25 US disclosed
US-6015575-A TRIAZINE, BENZOTRIAZOLE, BENZOPHENONE AND AMINOBENZOIC ACID DERIVATIVES AS RADIATION ABSORBERS CIBA SPECIALTY CHEMICALS CORPORATION (US) 2000-01-18 US disclosed
EP-0834304-A2 Liposomogenic UV absorbers Ciba SC Holding AG (CH) 1998-04-08 EP disclosed
EP-0815071-A1 LIPOSOMOGENIC UV ABSORBERS Ciba SC Holding AG (CH) 1998-01-07 EP disclosed
WO-1996029302-A1 LIPOSOMOGENIC UV ABSORBERS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 1996-09-26 WO disclosed