Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 3/20 | 0.34 |
| ▸ | IDH1 | O75874 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9408771 | 0.93 | NPC1 (0.38) | NPC1RAB9APOLBIDH1MEN1 | |
| SCHEMBL9408852 | 0.90 | NPC1 (0.36) | NPC1RAB9APOLBIDH1MEN1 | |
| SCHEMBL9408874 | 0.89 | NPC1 (0.35) | NPC1RAB9APOLBIDH1MEN1 | |
| SCHEMBL9408820 | 0.88 | NPC1 (0.44) | NPC1RAB9APOLBIDH1MEN1 | |
| SCHEMBL5679060 | 0.87 | NPC1 (0.35) | NPC1RAB9APOLBIDH1MEN1 | |
| SCHEMBL345190 | 0.87 | CNR2 (0.34) | NPC1RAB9APOLB | |
| SCHEMBL28501884 | 0.86 | NPC1 (0.33) | NPC1RAB9APOLBIDH1MEN1 | |
| SCHEMBL16191289 | 0.84 | POLB (0.36) | NPC1RAB9APOLBIDH1MEN1 | |
| SCHEMBL9408851 | 0.83 | NPC1 (0.38) | NPC1RAB9APOLBMEN1USP2 | |
| SCHEMBL5159425 | 0.83 | NPC1 (0.43) | NPC1RAB9APOLBIDH1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 653 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12595368-B2 | UV/HEVL-filtering contact lenses | ALCON INC. (CH) | 2026-04-07 | — | — | US | claimed |
| US-20250223392-A1 | HYDROPHILIZED POLYDIORGANOSILOXANE VINYLIC CROSSLINKERS AND USES THEREOF | ALCON INC (CH) | 2025-07-10 | — | — | US | claimed |
| US-12286501-B2 | Hydrophilized polydiorganosiloxane vinylic crosslinkers and uses thereof | ALCON INC. (CH) | 2025-04-29 | — | — | US | claimed |
| EP-4529621-A1 | UV/HEVL-FILTERING CONTACT LENSES | Alcon Inc. (CH) | 2025-04-02 | — | — | EP | claimed |
| CN-119137510-A | UV/HEVL filtering contact lenses | 爱尔康公司 | 2024-12-13 | — | — | CN | claimed |
| US-20240254269-A1 | HYDROPHILIZED POLYDIORGANOSILOXANE VINYLIC CROSSLINKERS AND USES THEREOF | ALCON INC. (CH) | 2024-08-01 | — | — | US | claimed |
| US-11926689-B2 | Hydrophilized polydiorganosiloxane vinylic crosslinkers and uses thereof | ALCON INC. (CH) | 2024-03-12 | — | — | US | claimed |
| WO-2023228055-A1 | UV/HEVL-FILTERING CONTACT LENSES | ALCON INC. (CH) | 2023-11-30 | — | — | WO | claimed |
| US-20230374306-A1 | UV/HEVL-FILTERING CONTACT LENSES | ALCON INC. (CH) | 2023-11-23 | — | — | US | claimed |
| EP-3303415-B1 | VISIBLE-LIGHT PHOTOINITIATORS AND USES THEREOF | ALCON INC (CH) | 2022-12-28 | — | — | EP | claimed |
| EP-2480927-A1 | PREPOLYMERS SUITABLE FOR MAKING ULTRA-VIOLET ABSORBING CONTACT LENSES | Novartis AG (CH) | 2012-08-01 | — | — | EP | claimed |
| EP-2432808-A1 | ACTINICALLY-CROSSLINKABLE SILOXANE-CONTAINING COPOLYMERS | Novartis AG (CH) | 2012-03-28 | — | — | EP | claimed |
| WO-2011034801-A1 | PREPOLYMERS SUITABLE FOR MAKING ULTRA-VIOLET ABSORBING CONTACT LENSES | NOVARTIS AG (CH) | 2011-03-24 | — | — | WO | claimed |
| US-20110063567-A1 | PREPOLYMERS SUITABLE FOR MAKING ULTRA-VIOLET ABSORBING CONTACT LENSES | ALCON INC. (CH) | 2011-03-17 | — | — | US | claimed |
| WO-2010133680-A1 | ACTINICALLY-CROSSLINKABLE SILOXANE-CONTAINING COPOLYMERS | NOVARTIS AG (CH) | 2010-11-25 | — | — | WO | claimed |
| US-20100296049-A1 | ACTINICALLY-CROSSLINKABLE SILOXANE-CONTAINING COPOLYMERS | ALCON INC. (CH) | 2010-11-25 | — | — | US | claimed |
| US-4861840-A | Novel siloxanyl acrylic monomer and gas-permeable contact lenses made therefrom | BARNES-HIND, INC. (US) | 1989-08-29 | — | — | US | claimed |
| EP-0293467-A1 | NOVEL SILOXANYL ACRYLIC MONOMER AND GAS-PERMEABLE CONTACT LENSES MADE THEREFROM | BARNES-HIND, INC. (US) | 1988-12-07 | — | — | EP | claimed |
| US-4787904-A | Hydrophillic intraocular lens | SEVERIN SANFORD L (US) | 1988-11-29 | — | — | US | claimed |
| WO-1988004299-A1 | NOVEL SILOXANYL ACRYLIC MONOMER AND GAS-PERMEABLE CONTACT LENSES MADE THEREFROM | BARNES-HIND, INC. (US) | 1988-06-16 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100296049-A1 | ACTINICALLY-CROSSLINKABLE SILOXANE-CONTAINING COPOLYMERS | VCL, MACF1, CFL1 | NPC1 3917/4885RAB9A 2881/4885POLB 2597/4885 |
| US-12595368-B2 | UV/HEVL-filtering contact lenses | UACA, HSPA4L, RAD54L | NPC1 3998/4885RAB9A 4835/4885POLB 3232/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.