Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.48 |
| ▸ | MAPT | P10636 | 5/20 | 0.48 |
| ▸ | RAB9A | P51151 | 4/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 4/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11032166 | 0.86 | NPC1 (0.54) | L3MBTL1MAPTRAB9AHTTTDP1 | |
| SCHEMBL10429427 | 0.86 | NPC1 (0.54) | L3MBTL1MAPTRAB9AHTTTDP1 | |
| SCHEMBL11034498 | 0.86 | NPC1 (0.54) | L3MBTL1MAPTRAB9AHTTTDP1 | |
| SCHEMBL11033127 | 0.86 | NPC1 (0.54) | L3MBTL1MAPTRAB9AHTTTDP1 | |
| SCHEMBL9876491 | 0.84 | ICMT (0.44) | MAPTRAB9AMEN1KMT2ATDP1 | |
| SCHEMBL9862969 | 0.83 | ICMT (0.44) | MAPTRAB9AMEN1KMT2ATDP1 | |
| SCHEMBL9863057 | 0.80 | TDP1 (0.41) | L3MBTL1MAPTRAB9AMEN1KMT2A | |
| SCHEMBL9667163 | 0.79 | TDP1 (0.38) | L3MBTL1MAPTRAB9AMEN1KMT2A | |
| SCHEMBL9666735 | 0.79 | TDP1 (0.38) | L3MBTL1MAPTRAB9AMEN1KMT2A | |
| SCHEMBL9668088 | 0.79 | TDP1 (0.38) | L3MBTL1MAPTRAB9AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0111345-A2 | Isoxazoles, useful as antiviral agents, and preparation thereof | STERLING DRUG INC. (US) | 1984-06-20 | — | — | EP | disclosed |
| US-4451476-A | Isoxazoles as antiviral agents | STERLING DRUG INC. (US) | 1984-05-29 | — | — | US | disclosed |