Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 14/20 | 0.54 |
| ▸ | RAB9A | P51151 | 13/20 | 0.54 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10429427 | 1.00 | NPC1 (0.54) | NPC1RAB9AS1PR4MAPTTDP1 | |
| SCHEMBL11034498 | 1.00 | NPC1 (0.54) | NPC1RAB9AS1PR4MAPTTDP1 | |
| SCHEMBL11033127 | 1.00 | NPC1 (0.54) | NPC1RAB9AS1PR4MAPTTDP1 | |
| SCHEMBL11035928 | 0.86 | L3MBTL1 (0.48) | NPC1RAB9AS1PR4MAPTTDP1 | |
| SCHEMBL11031814 | 0.86 | LMNA (0.47) | NPC1RAB9AS1PR4MAPTTDP1 | |
| SCHEMBL11032169 | 0.85 | RAB9A (0.45) | NPC1RAB9AMAPTTDP1L3MBTL1 | |
| SCHEMBL11034060 | 0.84 | NPC1 (0.44) | NPC1RAB9AMAPTTDP1L3MBTL1 | |
| SCHEMBL11031543 | 0.82 | MAPT (0.47) | NPC1RAB9AS1PR4MAPTTDP1 | |
| SCHEMBL9876491 | 0.81 | ICMT (0.44) | NPC1RAB9AS1PR4MAPTTDP1 | |
| SCHEMBL11031527 | 0.81 | ALDH1A1 (0.48) | NPC1RAB9AS1PR4MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4451476-A | Isoxazoles as antiviral agents | STERLING DRUG INC. (US) | 1984-05-29 | — | — | US | claimed |
| EP-0111345-A2 | Isoxazoles, useful as antiviral agents, and preparation thereof | STERLING DRUG INC. (US) | 1984-06-20 | — | — | EP | disclosed |
| US-4451476-A | Isoxazoles as antiviral agents | STERLING DRUG INC. (US) | 1984-05-29 | — | — | US | disclosed |