Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RNASEH1 | O60930 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 9/20 | 0.53 |
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 13/20 | 0.51 |
| ▸ | MEN1 | O00255 | 10/20 | 0.51 |
| ▸ | CASP6 | P55212 | 7/20 | 0.51 |
| ▸ | CASP3 | P42574 | 3/20 | 0.51 |
| ▸ | SENP8 | Q96LD8 | 3/20 | 0.51 |
| ▸ | SENP7 | Q9BQF6 | 3/20 | 0.51 |
| ▸ | SENP6 | Q9GZR1 | 3/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | APAF1 | O14727 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | CASP7 | P55210 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5873871 | 0.78 | NOTUM (0.51) | RNASEH1GAAKMT2AMEN1CASP6 | |
| SCHEMBL873778 | 0.76 | CASP3 (0.52) | KMT2AMEN1CASP3TDP1APAF1 | |
| SCHEMBL762397 | 0.76 | RNASEH1 (0.61) | RNASEH1GAATLR9PKMKMT2A | |
| SCHEMBL11850017 | 0.72 | HRH1 (0.70) | RNASEH1GAATLR9PKMKMT2A | |
| SCHEMBL3358267 | 0.72 | RNASEH1 (1.00) | RNASEH1GAATLR9PKMKMT2A | |
| SCHEMBL31720854 | 0.72 | RNASEH1 (0.61) | RNASEH1GAATLR9PKMKMT2A | |
| SCHEMBL16181505 | 0.72 | RNASEH1 (0.61) | RNASEH1GAATLR9PKMKMT2A | |
| SCHEMBL19577291 | 0.72 | RNASEH1 (0.61) | RNASEH1GAATLR9PKMKMT2A | |
| SCHEMBL9382466 | 0.72 | RNASEH1 (0.61) | RNASEH1GAATLR9PKMKMT2A | |
| SCHEMBL13495339 | 0.71 | RNASEH1 (0.56) | RNASEH1GAATLR9PKMKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-59128374-A | — | — | None | — | — | JP | disclosed |
| JP-S59128374-A | 2-SUBSTITUTED-1,2,3,4-TETRAHYDROISOQUINOLINE-1,3-DIONE DERIVATIVE AND ITS PREPARATION | HAMARI YAKUHIN KOGYO KK | 1984-07-24 | — | — | JP | disclosed |