Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RNASEH1 | O60930 | 1/20 | 1.00 |
| ▸ | GAA | P10253 | 6/20 | 0.58 |
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.58 |
| ▸ | PKM | P14618 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.57 |
| ▸ | MEN1 | O00255 | 5/20 | 0.57 |
| ▸ | APAF1 | O14727 | 3/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | CASP6 | P55212 | 6/20 | 0.53 |
| ▸ | CASP3 | P42574 | 3/20 | 0.51 |
| ▸ | SENP8 | Q96LD8 | 3/20 | 0.51 |
| ▸ | SENP7 | Q9BQF6 | 3/20 | 0.51 |
| ▸ | SENP6 | Q9GZR1 | 3/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | CASP1 | P29466 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | CASP7 | P55210 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25060904 | 0.77 | RNASEH1 (0.62) | RNASEH1 | |
| SCHEMBL23511723 | 0.77 | RNASEH1 (0.62) | RNASEH1GAATLR9PKMKMT2A | |
| Fluorene SCHEMBL4386551 | 0.76 | RNASEH1 (0.61) | RNASEH1GAATLR9PKMKMT2A | |
| SCHEMBL9382466 | 0.76 | RNASEH1 (0.61) | RNASEH1GAATLR9PKMKMT2A | |
| SCHEMBL19577291 | 0.76 | RNASEH1 (0.61) | RNASEH1GAATLR9PKMKMT2A | |
| SCHEMBL31720854 | 0.76 | RNASEH1 (0.61) | RNASEH1GAATLR9PKMKMT2A | |
| SCHEMBL762397 | 0.76 | RNASEH1 (0.61) | RNASEH1GAATLR9PKMKMT2A | |
| SCHEMBL16181505 | 0.76 | RNASEH1 (0.61) | RNASEH1GAATLR9PKMKMT2A | |
| SCHEMBL29836002 | 0.75 | RNASEH1 (0.60) | RNASEH1KMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL3195836 | 0.75 | RNASEH1 (0.60) | RNASEH1KMT2AMEN1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021103798-A1 | METHOD FOR PREPARING LACTONE COMPOUND | 浙江大学 | 2021-06-03 | — | — | WO | claimed |
| CN-110818671-B | Method for preparing lactone compounds | 浙江大学 | 2021-04-20 | — | — | CN | claimed |
| CN-110818671-A | Method for preparing lactone compounds | 浙江大学 | 2020-02-21 | — | — | CN | claimed |
| EP-2999789-B1 | METHOD FOR SELECTION OF HDIS3 PIN DOMAIN INHIBITORS AND USE OF HDIS3 PIN DOMAIN INHIBITORS FOR CANCER TREATMENT | INST BIOCHEMII I BIOFIZYKI POLSKIEJ AKADEMII NAUK (PL) | 2017-05-10 | — | — | EP | claimed |
| US-20160090639-A1 | Method for selection of hDIS3 PIN domain inhibitors and use of hDIS3 PIN domain inhibitors for cancer treatment | INSTYTUT BIOCHEMII I BIOFIZYKI POLSKIEJ AKADEMII NAUK (PL) | 2016-03-31 | — | — | US | claimed |
| EP-2999789-A1 | METHOD FOR SELECTION OF HDIS3 PIN DOMAIN INHIBITORS AND USE OF HDIS3 PIN DOMAIN INHIBITORS FOR CANCER TREATMENT | Instytut Biochemii I Biofizyki Polskiej Akademii Nauk (PL) | 2016-03-30 | — | — | EP | claimed |
| WO-2014188337-A1 | METHOD FOR SELECTION OF HDIS3 PIN DOMAIN INHIBITORS AND USE OF HDIS3 PIN DOMAIN INHIBITORS FOR CANCER TREATMENT | INSTYTUT BIOCHEMII I BIOFIZYKI POLSKIEJ AKADEMII NAUK (PL) | 2014-11-27 | — | — | WO | claimed |
| US-20250213569-A1 | METHODS AND COMPOSITIONS FOR MEASURING AND INHIBITING EXONUCLEASE ACTIVITY | NEW YORK UNIVERSITY (US) | 2025-07-03 | — | — | US | disclosed |
| US-20250123253-A1 | BORATE DETECTOR COMPOSITION AND ASSAY SOLUTION | Water Lens, LLC | 2025-04-17 | — | — | US | disclosed |
| EP-3307255-B1 | INHIBITORS OF NUCLEOTIDYL TRANSFERASES AND USE IN HERPES AND HEPATITIS VIRAL INFECTIONS THEREFOR | UNIV SAINT LOUIS (US) | 2024-11-20 | — | — | EP | disclosed |
| EP-3307256-B1 | HYDROXYLATED TROPOLONE INHIBITORS OF NUCLEOTIDYL TRANSFERASES IN HERPESVIRUS AND HEPATITIS B | UNIV SAINT LOUIS (US) | 2023-06-07 | — | — | EP | disclosed |
| US-20230041027-A1 | BORATE DETECTOR COMPOSITION AND ASSAY SOLUTION | Water Lens, LLC | 2023-02-09 | — | — | US | disclosed |
| US-11420922-B2 | Hydroxylated tropolone inhibitors of nucleotidyl transferases in herpesvirus and Hepatitis B and uses therefor | SAINT LOUIS UNIVERSITY (US) | 2022-08-23 | — | — | US | disclosed |
| US-8329377-B2 | Imide compound and chemically amplified resist composition containing the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-12-11 | — | — | US | disclosed |
| US-8329377-B2 | Imide compound and chemically amplified resist composition containing the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-12-11 | — | — | US | disclosed |
| WO-2012167011-A1 | DSRNA/DNA HYBRID GENOME REPLICATION INTERMEDIATE OF METAKARYOTIC STEM CELLS | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2012-12-06 | — | — | WO | disclosed |
| WO-2012085003-A1 | 2-HYDROXYISOQUINOLINE-1,3(2H,4H)-DIONES AND RELATED COMPOUNDS USEFUL AS HIV REPLICATION INHIBITORS | KATHOLIEKE UNIVERSITEIT LEUVEN, K.U. LEUVEN R&D (BE) | 2012-06-28 | — | — | WO | disclosed |
| US-20100028807-A1 | Imide Compound and Chemically Amplified Resist Composition Containing The Same | SUMITOMO CHEMICAL COMPANY, LTD. (JP) | 2010-02-04 | — | — | US | disclosed |
| US-20100028807-A1 | Imide Compound and Chemically Amplified Resist Composition Containing The Same | SUMITOMO CHEMICAL COMPANY, LTD. (JP) | 2010-02-04 | — | — | US | disclosed |
| US-20100028807-A1 | Imide Compound and Chemically Amplified Resist Composition Containing The Same | SUMITOMO CHEMICAL COMPANY, LTD. (JP) | 2010-02-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160090639-A1 | Method for selection of hDIS3 PIN domain inhibitors and use of hDIS3 PIN domain inhibitors for cancer treatment | PIN4, DDB1, HIRIP3 | RNASEH1 470/4885GAA 4115/4885TLR9 4812/4885 |
| US-20250213569-A1 | METHODS AND COMPOSITIONS FOR MEASURING AND INHIBITING EXONUCLEASE ACTIVITY | DCLRE1B, RNASE1, ADAR | RNASEH1 21/4885GAA 91/4885TLR9 2232/4885 |
| US-20100028807-A1 | Imide Compound and Chemically Amplified Resist Composition Containing The Same | IGF1R, CCNA1, MYC | RNASEH1 239/4885GAA 4611/4885TLR9 1027/4885 |
| US-11420922-B2 | Hydroxylated tropolone inhibitors of nucleotidyl transferases in herpesvirus and Hepatitis B and uses therefor | TYMP, TYMS, DNTT | RNASEH1 439/4885GAA 287/4885TLR9 3157/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.