Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | AADAT | Q8N5Z0 | 6/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.35 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | GOT1 | P17174 | 1/20 | 0.34 |
| ▸ | KYAT1 | Q16773 | 1/20 | 0.34 |
| ▸ | KYAT3 | Q6YP21 | 1/20 | 0.34 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7846754 | 0.70 | ALDH1A1 (0.42) | MEN1KMT2AALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL13818358 | 0.67 | MEN1 (0.48) | MEN1KMT2AALDH1A1AADATPOLB | |
| SCHEMBL9326542 | 0.64 | ALDH1A1 (0.58) | ALDH1A1POLBLMNAMT-CO2ALOX5 | |
| SCHEMBL5193387 | 0.64 | MEN1 (0.50) | MEN1KMT2AALDH1A1POLBNPC1 | |
| SCHEMBL6918067 | 0.64 | ALDH1A1 (0.58) | ALDH1A1POLBLMNAMT-CO2ALOX5 | |
| SCHEMBL7933807 | 0.64 | MEN1 (0.50) | MEN1KMT2AALDH1A1POLBNPC1 | |
| SCHEMBL7927546 | 0.64 | MEN1 (0.50) | MEN1KMT2AALDH1A1POLBNPC1 | |
| SCHEMBL24776903 | 0.64 | MGLL (0.44) | MEN1KMT2AALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL27528485 | 0.63 | MEN1 (0.35) | MEN1KMT2AALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL2010660 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4552585-A | Herbicidal 2-(aminophenyl)methyl derivatives of 3-isoxazolidinones or 3-oxazinones | FMC CORPORATION (US) | 1985-11-12 | — | — | US | disclosed |