Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | AADAT | Q8N5Z0 | 4/20 | 0.40 |
| ▸ | F2 | P00734 | 1/20 | 0.40 |
| ▸ | PLG | P00747 | 1/20 | 0.40 |
| ▸ | ELANE | P08246 | 1/20 | 0.40 |
| ▸ | CTSG | P08311 | 1/20 | 0.40 |
| ▸ | CMA1 | P23946 | 1/20 | 0.40 |
| ▸ | CTRC | Q99895 | 1/20 | 0.40 |
| ▸ | EP300 | Q09472 | 1/20 | 0.39 |
| ▸ | GSK3A | P49840 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
| ▸ | MGLL | Q99685 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18740588 | 0.84 | KMT2A (0.41) | ALDH1A1KMT2AMEN1SMN1; SMN2GAA | |
| SCHEMBL18740497 | 0.84 | ALDH1A1 (0.41) | ALDH1A1KMT2AMEN1F2CYP1A2 | |
| SCHEMBL18740496 | 0.84 | ALDH1A1 (0.41) | ALDH1A1KMT2AMEN1F2CYP1A2 | |
| SCHEMBL18740587 | 0.84 | KMT2A (0.41) | ALDH1A1KMT2AMEN1SMN1; SMN2GAA | |
| Hydrochloric Acid SCHEMBL18740595 | 0.83 | ALDH1A1 (0.41) | ALDH1A1KMT2AF2DRD2 | |
| Hydrochloric Acid SCHEMBL18740594 | 0.83 | ALDH1A1 (0.41) | ALDH1A1KMT2AF2DRD2 | |
| SCHEMBL2687303 | 0.82 | HTT (0.46) | ALDH1A1KMT2AMEN1GAA | |
| SCHEMBL9566068 | 0.74 | KMT2A (0.42) | KMT2AMEN1SMN1; SMN2DRD2DRD4 | |
| SCHEMBL2010924 | 0.71 | — | — | |
| SCHEMBL11036458 | 0.70 | MEN1 (0.38) | ALDH1A1KMT2AMEN1AADATCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0535645-B1 | Carbamate derivatives of 4-amino-3-isoxazolidinones and 3-amino-1-hydroxypyrrolidin-2-ones, a process for their preparation and their use as medicaments | AVENTIS PHARMA INC (US) | 2001-05-09 | — | — | EP | disclosed |
| EP-1069125-A2 | Carbamate derivatives of 4-amino-3-isoxazolidinones, 3-amino-1-hydroxypyrrolidin-2-ones and 1-amino-1-cyclopropanecarboxylic acid analogs, a process for their preparation and their use as medicaments | AVENTIS PHARMACEUTICALS INC. (US) | 2001-01-17 | — | — | EP | disclosed |
| US-5234941-A | Cognition activators; Alzheimer's disease; cholinergic agents; acetylchloinesterase inhibitors | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1993-08-10 | — | — | US | disclosed |
| US-5231093-A | Carbamate derivatives of 4-amino-3-isoxazolidinones, 3-amino-1-hydroxypyrrolidin-2-ones and 1-amino-1-cyclopropanecarboxylic acid analogs | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1993-07-27 | — | — | US | disclosed |
| EP-0535645-A2 | Carbamate derivatives of 4-amino-3-isoxazolidinones, 3-amino-1-hydroxypyrrolidin-2-ones and 1-amino-1-cyclopropanecarboxylic acid analogs, a process for their preparation and their use as medicaments | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1993-04-07 | — | — | EP | disclosed |
| US-5153193-A | Nootropic, cholinergic agents | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1992-10-06 | — | — | US | disclosed |
| US-4826527-A | Aminophenylmethyl isoxazolidinones as plant regulators | FMC CORPORATION (US) | 1989-05-02 | — | — | US | disclosed |