Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G4A | P47712 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 4/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7874916 | 0.76 | MAPT (0.55) | KMT2ANR1I2MAPTFGFR1LMNA | |
| SCHEMBL2361153 | 0.74 | HPGD (0.63) | PLA2G4ANR1I2MAPTFGFR1LMNA | |
| SCHEMBL18250739 | 0.73 | LMNA (0.59) | KMT2ANR1I2MAPTFGFR1LMNA | |
| SCHEMBL9853306 | 0.73 | LMNA (0.59) | KMT2ANR1I2MAPTFGFR1LMNA | |
| SCHEMBL9038430 | 0.73 | LMNA (0.59) | KMT2ANR1I2MAPTFGFR1LMNA | |
| SCHEMBL9853312 | 0.73 | LMNA (0.59) | KMT2ANR1I2MAPTFGFR1LMNA | |
| SCHEMBL9041559 | 0.73 | LMNA (0.59) | KMT2ANR1I2MAPTFGFR1LMNA | |
| SCHEMBL3806522 | 0.73 | HDAC1 (0.51) | KMT2AMAPTLMNASMN1; SMN2HTT | |
| SCHEMBL20377243 | 0.72 | PLA2G4A (0.58) | PLA2G4AFGFR1TP53TSHR | |
| SCHEMBL19848227 | 0.72 | MAPT (0.58) | MAPTFGFR1LMNASMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4492708-A | Antiviral benzimidazoles | ELI LILLY AND COMPANY (US) | 1985-01-08 | — | — | US | disclosed |
| EP-0111993-A2 | Improvements in or relating to benzimidazoles | ELI LILLY AND COMPANY (US) | 1984-06-27 | — | — | EP | disclosed |