Benzene

Benzene

SCHEMBL11037140

O=C(O)OCCOC(=O)O.c1ccccc1

nearest known ligand 0.42

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 3/20 0.42
LMNA P02545 2/20 0.38
TSHR P16473 3/20 0.36
THRB P10828 1/20 0.35
HCAR2 Q8TDS4 1/20 0.35
NPC1 O15118 4/20 0.34
RAB9A P51151 4/20 0.34
SMN1; SMN2 Q16637 3/20 0.34
ESR1 P03372 1/20 0.34
ESR2 Q92731 1/20 0.34
ALDH1A1 P00352 3/20 0.33
SERPINE1 P05121 1/20 0.33
TP53 P04637 1/20 0.33
GLA P06280 1/20 0.33
CYP3A4 P08684 1/20 0.33
HPGD P15428 1/20 0.33
MAPK1 P28482 1/20 0.33
HIF1A Q16665 1/20 0.33
HSD17B10 Q99714 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20649 0.93 ALDH1A1 (0.35) TDP1LMNATSHRHCAR2ALDH1A1
Water SCHEMBL2471732 0.89 ALDH1A1 (0.33) TDP1LMNATSHRALDH1A1TP53
Ammonia Solution, Strong SCHEMBL5487461 0.89 ALDH1A1 (0.33) TDP1LMNATSHRALDH1A1TP53
Bicarbonate SCHEMBL177964 0.89 CA1 (0.39) TDP1LMNATSHRALDH1A1TP53
Hydrazine SCHEMBL10344909 0.86 TSHR (0.33) TDP1LMNATSHRTHRBALDH1A1
Methyl Alcohol SCHEMBL1326721 0.86 ALDH1A1 (0.38) TDP1LMNATSHRTHRBHCAR2
Ethylene SCHEMBL8927826 0.86 TSHR (0.38) TDP1TSHRTHRBALDH1A1TP53
Benzene SCHEMBL10423969 0.84 KMT2A (0.40) TDP1LMNATSHRSMN1; SMN2TP53
Methoxymethane SCHEMBL5955384 0.83 ALDH1A1 (0.36) TDP1LMNATSHRTHRBHCAR2
Carbamic Acid SCHEMBL5450545 0.83 ACHE (0.47) TDP1LMNATSHRTHRBALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0149133-A2 Polyacetylene composite, process for production thereof, and method for use thereof Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1985-07-24 EP disclosed