Known targets — ChEMBL curated mechanism
ABCC9ABL1ACEACHEACVR1ADORA1ADORA2AADORA2BADORA3ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALOX5ATP4AATP4BBCRBTKCACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGCRBNCUL4ACXCR1CXCR2DDB1DDCDHFRDPP4DRD2DRD3DRD4EGFRERBB2ERBB4ESR1ESR2FDPSFKBP1AFLT1FLT3FLT4GARTGHSRGRIA1GRIA2GRIA3GRIA4GRIK1GRIK2GRIK3GRIK4GRIK5GRIN2AGSK3AGSK3BHDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IDH1IDH2IMPA1ITGA2BITGB3JAK1JAK2JAK3KCNJ11KCNK3KCNK9KDRKITMEN1METMMP1MMP13MMP7MMP8NANOD2NS5bODC1OPG057OPRD1OPRK1OPRM1PPARP1PARP2PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PKLRPPARDPPATPTGS1PTGS2RBX1ROCK1ROCK2RRM1RRM2RRM2BSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC10A2SLC5A2SLC6A2SLC6A3SLC6A4SLC9A3SYKTACR1THRATHRBTOP1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYK2TYMSVDRampCblablaT-3blaT-4blaT-5blaT-6blaUOE-1dacAdacBdacCfolAfolPftsIgyrAgyrBileSmecAmrcAmrcBmrdAparCparEpbp2pbp4pbpApbpFrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUthyAykgMykgO
The experimentally established mechanism targets of Water. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | DGKA | P23743 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20649 | 0.96 | ALDH1A1 (0.35) | ALDH1A1TSHRTP53HIF1ATDP1 | |
| Bicarbonate SCHEMBL177964 | 0.92 | CA1 (0.39) | ALDH1A1TSHRTP53HIF1ATDP1 | |
| Ammonia Solution, Strong SCHEMBL5487461 | 0.92 | ALDH1A1 (0.33) | ALDH1A1TSHRTP53HIF1ATDP1 | |
| Hydrazine SCHEMBL10344909 | 0.89 | TSHR (0.33) | ALDH1A1TSHRTP53HIF1ATDP1 | |
| Ethylene SCHEMBL8927826 | 0.89 | TSHR (0.38) | ALDH1A1TSHRTP53HIF1ATDP1 | |
| Methyl Alcohol SCHEMBL1326721 | 0.89 | ALDH1A1 (0.38) | ALDH1A1TSHRTP53HIF1ATDP1 | |
| Benzene SCHEMBL11037140 | 0.89 | TDP1 (0.42) | ALDH1A1TSHRTP53HIF1ATDP1 | |
| Methoxymethane SCHEMBL5955384 | 0.86 | ALDH1A1 (0.36) | ALDH1A1TSHRTP53HIF1ATDP1 | |
| SCHEMBL20550573 | 0.86 | ALDH1A1 (0.36) | ALDH1A1TSHRTP53HIF1ATDP1 | |
| SCHEMBL22129561 | 0.86 | ALDH1A1 (0.48) | ALDH1A1TSHRTP53HIF1ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021230917-A2 | HYDROCARBON PYROLYSIS WITH LESS EXHAUST EMISSION | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2021-11-18 | — | — | WO | disclosed |
| WO-2021138093-A2 | PYROLYSIS PRODUCT COMPRESSION USING CO2 LOOP | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2021-07-08 | — | — | WO | disclosed |
| EP-1555705-B1 | Cathode active material for lithium rechargeable battery and lithium rechargeable battery using the same | SAMSUNG SDI CO LTD (KR) | 2011-10-05 | — | — | EP | disclosed |
| EP-1555705-A2 | Cathode active material for lithium rechargeable battery and lithium rechargeable battery using the same | Samsung SDI Co., Ltd. (KR) | 2005-07-20 | — | — | EP | disclosed |