Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.45 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | EGFR | P00533 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27828181 | 0.81 | NSD2 (0.46) | KCNQ3KCNQ2KMT2ACACNA1BHDAC1 | |
| SCHEMBL31210057 | 0.80 | MAPT (0.48) | L3MBTL1KMT2AMAPTMEN1KDM4E | |
| SCHEMBL10549460 | 0.77 | MAPT (0.51) | L3MBTL1KMT2AMAPTMEN1ALDH1A1 | |
| SCHEMBL20232562 | 0.77 | ALDH1A1 (0.42) | L3MBTL1EGFRMAPTKDM4EALDH1A1 | |
| SCHEMBL10055049 | 0.77 | ALDH1A1 (0.55) | L3MBTL1KMT2AHDAC1MAPTMEN1 | |
| SCHEMBL11036299 | 0.74 | MAPT (0.53) | L3MBTL1KCNQ3KCNQ2KMT2AEGFR | |
| SCHEMBL9134263 | 0.74 | HDAC1 (0.49) | KMT2ACACNA1BHDAC1MAPTMEN1 | |
| SCHEMBL4430410 | 0.73 | KCNQ2 (0.78) | L3MBTL1KCNQ3KCNQ2KMT2AMAPT | |
| SCHEMBL2476416 | 0.73 | KDM4E (0.47) | L3MBTL1EGFRMAPTKDM4EALDH1A1 | |
| SCHEMBL20837291 | 0.73 | NCF1 (0.44) | L3MBTL1KMT2AEGFRMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0151826-A1 | 4-[(Bicyclic heterocyclyl)-methyl and -hetero]-piperidines | JANSSEN PHARMACEUTICA N.V. (BE) | 1985-08-21 | — | — | EP | disclosed |