Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | DDB1 | Q16531 | 2/20 | 0.44 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.44 |
| ▸ | MMP2 | P08253 | 2/20 | 0.38 |
| ▸ | MMP1 | P03956 | 1/20 | 0.38 |
| ▸ | MMP3 | P08254 | 1/20 | 0.38 |
| ▸ | MMP7 | P09237 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 3/20 | 0.35 |
| ▸ | MMP9 | P14780 | 1/20 | 0.35 |
| ▸ | MMP8 | P22894 | 1/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.33 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11037176 | 0.88 | SMN1; SMN2 (0.44) | SMN1; SMN2GAADDB1CRBNMEN1 | |
| SCHEMBL11311666 | 0.81 | MGLL (0.43) | SMN1; SMN2DDB1CRBNMEN1KMT2A | |
| SCHEMBL8536487 | 0.80 | MCL1 (0.49) | SMN1; SMN2GAADDB1CRBNMEN1 | |
| SCHEMBL8533046 | 0.80 | MCL1 (0.49) | SMN1; SMN2GAADDB1CRBNMEN1 | |
| SCHEMBL8533043 | 0.80 | MCL1 (0.49) | SMN1; SMN2GAADDB1CRBNMEN1 | |
| SCHEMBL993051 | 0.80 | MCL1 (0.45) | SMN1; SMN2GAAMEN1KMT2APOLB | |
| SCHEMBL10531994 | 0.79 | MCL1 (0.44) | SMN1; SMN2GAAMEN1KMT2AMCL1 | |
| SCHEMBL1933595 | 0.79 | MCL1 (0.44) | SMN1; SMN2GAAMEN1KMT2AMCL1 | |
| SCHEMBL8028222 | 0.78 | MCL1 (0.39) | SMN1; SMN2GAAMEN1KMT2APOLB | |
| SCHEMBL598825 | 0.78 | SMN1; SMN2 (0.44) | SMN1; SMN2MEN1KMT2AMCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0885869-A1 | THERAPEUTIC AGENT FOR DIABETES | Japan Tobacco Inc. (JP) | 1998-12-23 | — | — | EP | disclosed |