Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD1 | P21728 | 2/20 | 0.39 |
| ▸ | DRD5 | P21918 | 2/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.37 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.36 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
| ▸ | CASR | P41180 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11041485 | 0.78 | BRD4 (0.44) | EGFRMAPK1NPSR1POLBGRM2 | |
| SCHEMBL11040818 | 0.76 | NPSR1 (0.46) | NPSR1POLBBLMADORA1ALDH1A1 | |
| SCHEMBL11037216 | 0.76 | GRIN2D (0.41) | MAPK1NPSR1GRM2ALDH1A1MAPT | |
| SCHEMBL11040857 | 0.75 | DRD1 (0.41) | DRD1DRD5EGFRPOLBGRM2 | |
| SCHEMBL10743293 | 0.72 | MTNR1B (0.42) | EGFRMAPK1NPSR1POLBGRM2 | |
| SCHEMBL4619699 | 0.66 | BRD4 (0.66) | POLBGRM2ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL30293254 | 0.66 | BRD4 (0.66) | POLBGRM2ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL26870466 | 0.63 | PIK3CA (0.47) | DRD1DRD5EGFRPOLBGRM2 | |
| SCHEMBL15043471 | 0.62 | POLB (0.48) | MAPK1POLBGRM2ALDH1A1MAPT | |
| SCHEMBL26697997 | 0.62 | PIK3CA (0.48) | EGFRPOLBGRM2ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0040401-B1 | TRIAZOLOQUINOXALIN-4-ONES AND SUCH OXALINE-4-THIONES | USV PHARMACEUTICAL CORPORATION (US) | 1984-03-21 | — | — | EP | disclosed |
| US-4354027-A | HYPOTENSIVE AGENTS | USV PHARMACEUTICAL CORPORATION (US) | 1982-10-12 | — | — | US | disclosed |
| EP-0040401-A1 | Triazoloquinoxalin-4-ones and such oxaline-4-thiones | USV PHARMACEUTICAL CORPORATION (US) | 1981-11-25 | — | — | EP | disclosed |