Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD1 | P21728 | 1/20 | 0.41 |
| ▸ | DRD5 | P21918 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 4/20 | 0.38 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.38 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | BRD2 | P25440 | 1/20 | 0.35 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.35 |
| ▸ | BRDT | Q58F21 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11037216 | 0.84 | GRIN2D (0.41) | GRM2KDM4EALDH1A1MAPTHPGD | |
| SCHEMBL11041485 | 0.81 | BRD4 (0.44) | BRD4GRM2BRPF1ALDH1A1MAPT | |
| SCHEMBL11040818 | 0.75 | NPSR1 (0.46) | BRD4KDM4EALDH1A1MAPTHPGD | |
| SCHEMBL11037212 | 0.75 | DRD1 (0.39) | DRD1DRD5GRM2KDM4EALDH1A1 | |
| SCHEMBL10743293 | 0.71 | MTNR1B (0.42) | GRM2KDM4EALDH1A1MAPTADORA1 | |
| SCHEMBL11037267 | 0.67 | GRIN2D (0.48) | — | |
| SCHEMBL11037260 | 0.66 | HTR2C (0.49) | ADORA1 | |
| SCHEMBL30293254 | 0.65 | BRD4 (0.66) | BRD4GRM2BRPF1KDM4EALDH1A1 | |
| SCHEMBL4619699 | 0.65 | BRD4 (0.66) | BRD4GRM2BRPF1KDM4EALDH1A1 | |
| SCHEMBL15043471 | 0.65 | POLB (0.48) | GRM2KDM4EALDH1A1MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0040401-B1 | TRIAZOLOQUINOXALIN-4-ONES AND SUCH OXALINE-4-THIONES | USV PHARMACEUTICAL CORPORATION (US) | 1984-03-21 | — | — | EP | disclosed |
| US-4354027-A | HYPOTENSIVE AGENTS | USV PHARMACEUTICAL CORPORATION (US) | 1982-10-12 | — | — | US | disclosed |
| EP-0040401-A1 | Triazoloquinoxalin-4-ones and such oxaline-4-thiones | USV PHARMACEUTICAL CORPORATION (US) | 1981-11-25 | — | — | EP | disclosed |